NOVARTIS

NOVARTIS logo
🇨🇭Switzerland
Ownership
Public, Private
Established
1996-01-01
Employees
76K
Market Cap
$242.6B
Website
https://www.novartis.com/our-science/novartis-institutes-biomedical-research
targetedonc.com
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KEYNOTE-006 Study of Pembrolizumab Shows Continued Survival Benefits in Advanced Melanoma

Pembrolizumab (Keytruda) showed sustained survival benefits over ipilimumab (Yervoy) in unresectable stage III or IV melanoma patients, with 10-year follow-up data from the KEYNOTE-006 study presented at the 2024 ESMO Congress. Pembrolizumab had a median overall survival (OS) of 32.7 months vs 15.9 months for ipilimumab, with 8- and 10-year OS rates of 36.9% and 34.0% vs 24.8% and 23.6%, respectively. The study also highlighted the safety profile and long-term efficacy of pembrolizumab, supporting its standard of care status in advanced melanoma.
ansto.gov.au
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Remarkable clinical trial results shared internationally

Peter Macallum Cancer Centre's UpFrontPSMA study shows LuPSMA therapy significantly improves outcomes for newly diagnosed prostate cancer patients, with 41% achieving undetectable PSA at 48 weeks compared to 16% with standard-of-care. The results were published in *Lancet Oncology* and presented at ESMO 2024.
miragenews.com
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Clinical Trial Breakthrough Shared Globally

Peter Macallum Cancer Centre's UpFrontPSMA study shows LuPSMA therapy significantly improves outcomes in newly diagnosed metastatic prostate cancer patients, outperforming standard chemotherapy alone. The trial, funded by Prostate Cancer Research Alliance, involved 130 patients from 11 Australian hospitals and was presented at ESMO 2024. ANSTO supplies the Lutetium-177 isotope used in the therapy.

Austria wants to be at the top of the podium in research and development

In 2023, Austria's R&D expenditure was 3.26% of GDP, ranking 3rd in the EU. By 2024, it's projected to reach 3.34%, totaling €16.64 billion. Tyrol is a life sciences hub, with Novartis expanding its facilities at a cost of €250 million each by 2025. Novartis focuses on innovative medicines, opening the Analytics Lab in Kundl and CC2Plus in Schaftenau. Ligand Pharmaceuticals acquired Apeiron Biologics in July 2024, committing to invest up to USD 4 million in invIOs GmbH. Austria promotes R&D through direct funding, a 14% research tax credit, and an immigration allowance. The Austrian Business Agency offers free advice and will participate in major biotech conferences.
thirdeyenews.in
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United States Translational Regenerative Medicine Market By Application

The U.S. Translational Regenerative Medicine Market is projected to grow from USD xx.x Billion in 2023 to USD xx.x Billion by 2031, with a CAGR of xx.x%. Key applications include orthopedics, cardiovascular, oncology, wound healing, and others. Major manufacturers include Athersys, Avita Medical, AxoGen, and more. The market's future is promising yet complex, with regional variations and emerging trends.
onclive.com
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Early Switch Therapy to Atezolizumab After Vemurafenib/Cobimetinib Run-in Improves OS

Early switch to atezolizumab after vemurafenib plus cobimetinib in BRAF V600-positive melanoma showed improved OS at 4 and 5 years in the ImmunoCobiVem trial, but not statistically significant. Rapid progression after switch to immune checkpoint inhibition was observed in some patients.
onclive.com
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Long-Term KEYNOTE-006 Data Support Pembrolizumab as SOC in Advanced Melanoma

Pembrolizumab (Keytruda) showed improved survival over ipilimumab (Yervoy) in stage III/IV melanoma patients, with 10-year OS rates of 34% vs 23.6% and MSS rates of 45.2% vs 31.3%. Pembrolizumab's median OS was 32.7 months vs 15.9 months for ipilimumab, and median modified PFS was 9.4 months vs 3.8 months. Patients who responded well to initial pembrolizumab treatment had significant long-term benefits, with 80% OS rate after 94 weeks of treatment. These results support pembrolizumab as a standard care for advanced melanoma.
medcitynews.com
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Roche Welcomes FDA Approvals for Injectable Versions of MS and Cancer Drugs

FDA approves subcutaneous versions of Roche's biologic drugs: Tecentriq Hybreza for cancer (7-min injection, 3.8B Swiss francs revenue) and Ocrevus Zunovo for MS (10-min injection, 6.4B Swiss francs revenue), both offering faster dosing times and broader accessibility.
roswellpark.org
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Roswell Park-Designed Treatment Regimen Doubles Progression-Free Survival in Metastatic Kidney Cancer

A phase 1/2 trial for metastatic kidney cancer showed a novel two-agent regimen at Roswell Park doubled progression-free survival compared to single-agent treatment, with median PFS of 23.3 months versus 11.1 months.
meramandsaur.in
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North America Clozapine Tablet Market By Application

The North America Clozapine Tablet market, driven by tech advancements and data-driven decisions, is segmented by applications like schizophrenia, bipolar disorder, resistant depression, and psychotic disorders. Key manufacturers include Mylan, Novartis, and Teva Pharmaceuticals. The market's future is promising, with strategic adaptation to emerging trends crucial for growth.
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