UNIVERSITY OF ALABAMA AT BIRMINGHAM

Post hoc analysis of pooled BOREAS and NOTUS phase 3 trials demonstrates dupilumab's consistent efficacy in reducing COPD exacerbations by 31-33% regardless of cardiovascular or metabolic disease history.

A randomized clinical trial of 249 participants found that a single injection of benzathine penicillin G achieved 76% serologic response compared to 70% with the three-dose regimen at 6 months.

Alveolus Bio announced a strategic financing round led by Shilpa Medicare Limited, positioning the company for Phase 2 clinical trials and first-in-human studies of its respiratory therapeutics platform.

The FDA has granted Orphan Drug Designation to Mustang Bio's MB-101 CAR-T therapy for treating astrocytomas and glioblastoma, providing seven years of market exclusivity and development incentives.

The FDA has approved Darmiyan's 7-year post-market surveillance study for BrainSee, the first FDA-approved AI-powered tool that predicts Alzheimer's disease progression in patients with mild cognitive impairment.

A retrospective study of 1,552 diabetic patients found that GLP-1 receptor agonist use after PCI for acute myocardial infarction reduced 3-year all-cause mortality by 26% compared to non-users.

GeoVax has strengthened its Gedeptin therapy platform with newly allowed patent claims covering the synergistic combination of gene therapy with radiation for treating various solid tumors.

City of Hope has initiated a phase 1/2 clinical trial investigating whether denosumab, an FDA-approved osteoporosis medication, can protect and regenerate insulin-producing beta cells in early-stage type 1 diabetes patients.

UAB researchers initiate NIH-funded clinical trial comparing three diabetes treatments - Metformin, Insulin Glargine, and experimental drug Dorzagliatin - to evaluate their effectiveness on nocturnal blood sugar control.

The University of Alabama at Birmingham (UAB) is conducting a clinical trial to evaluate a novel on-demand PrEP rectal douche.