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UNIVERSITY OF ALABAMA AT BIRMINGHAM

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1969-01-01

Employees: 2K

Market Cap: -

Website: http://www.uab.edu

Clinical Trials

Precision Medicine in Anesthesia: Genetic Component in Opioid-induced Respiratory Depression

Terminated

Conditions: Respiratory Depression

Interventions: Drug: Fentanyl

First Posted Date: 2018-02-22

Last Posted Date: 2025-05-25

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 26

Registration Number: NCT03441282

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis

Early Phase 1

Recruiting

Conditions: Chronic Rhinosinusitis (Diagnosis)

Interventions: Drug: Ivacaftor
Drug: standard of care treatment

First Posted Date: 2018-02-20

Last Posted Date: 2025-04-16

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 20

Registration Number: NCT03439865

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

Healthy Homes, Healthy Habits

Not Applicable

Completed

Conditions: Obesity; Familial
Obesity
Obesity, Childhood

Interventions: Behavioral: Home visitation + HABITS program
Behavioral: Standard home visitation program

First Posted Date: 2018-02-14

Last Posted Date: 2024-10-29

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 296

Registration Number: NCT03433456

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

A Novel Regimen to Prevent Malaria and STI in Pregnant Women With HIV

Phase 2

Completed

Conditions: Sexually Transmitted Infection
HIV
Pregnancy Malaria

Interventions: Drug: Azithromycin/TMPS
Drug: Placebo/TMPS

First Posted Date: 2018-02-13

Last Posted Date: 2023-11-27

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 308

Registration Number: NCT03431168

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

Use of 5.0% Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye Disease in Contact Lens Wearers

Phase 4

Withdrawn

Conditions: Contact Lens Dry Eye

Interventions: Drug: Lifitegrast

First Posted Date: 2018-02-13

Last Posted Date: 2018-10-25

Lead Sponsor: University of Alabama at Birmingham

Registration Number: NCT03431272

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid

Not Applicable

Completed

Conditions: Type 2 Diabetes Mellitus

Interventions: Other: Low Glycemic Diet
Other: Control Diet

First Posted Date: 2018-02-12

Last Posted Date: 2024-10-24

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 65

Registration Number: NCT03430310

Locations: 🇺🇸
The University of Alabama at Birmingham, Birmingham, Alabama, United States

Assessment of the Efficacy of the Aerodentis System

Not Applicable

Completed

Conditions: Orthodontic Treatment
Orthodontics
Tooth Crowding

Interventions: Device: Aerodentis system
Device: Invisalign clear aligner system

First Posted Date: 2018-02-05

Last Posted Date: 2020-11-04

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 45

Registration Number: NCT03421886

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

A Dose Escalation Trial of Five Fraction Stereotactic Radiation Therapy for Brain Metastases

Not Applicable

Active, not recruiting

Conditions: Brain Metastases

Interventions: Radiation: Dose Escalated Five Fraction Stereotactic Radiosurgery

First Posted Date: 2018-01-26

Last Posted Date: 2025-05-16

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 13

Registration Number: NCT03412812

Locations: 🇺🇸
Hazelrig-Salter Radiation Oncology Center, Birmingham, Alabama, United States

Quadratus Lumborum Block Versus Control for Total Hip Arthroplasty

Phase 2

Completed

Conditions: Total Hip Arthroplasty

Interventions: Drug: Quadratus Lumborum Block (QLB)
Drug: Standard of Care

First Posted Date: 2018-01-24

Last Posted Date: 2021-06-09

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 80

Registration Number: NCT03408483

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

Unlocking Dystonia From Parkinson's Disease With Directional DBS Technology

Not Applicable

Completed

Conditions: Dystonia-Parkinsonism, Adult-Onset
Parkinson Disease

Interventions: Device: Boston Scientific Vercise PC IPG with directional DBS lead

First Posted Date: 2018-01-24

Last Posted Date: 2022-11-10

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 38

Registration Number: NCT03409120

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

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