THE BRIGHAM AND WOMEN'S HOSPITAL, INC.

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea

Phase 1

Completed

Conditions: Sleep Apnea

Interventions: Drug: SAS0421a
Drug: SAS0421c
Drug: placebo
Drug: SAS0421b

First Posted Date: 2019-03-27

Last Posted Date: 2022-03-02

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 23

Registration Number: NCT03892772

Locations: 🇦🇺
Monash University, Clayton, Victoria, Australia
🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States

A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

Not Applicable

Recruiting

Conditions: Amputation

Interventions: Procedure: Standard amputation procedure
Procedure: Modified amputation procedure

First Posted Date: 2019-03-20

Last Posted Date: 2025-02-05

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 20

Registration Number: NCT03882073

Locations: 🇺🇸
Walter Reed National Military Medical Center, Bethesda, Maryland, United States
🇺🇸
Brigham & Women's Hospital, Boston, Massachusetts, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

and more 1 locations

Low Intensity Focused Ultrasound Epilepsy: A Pilot Trial

Not Applicable

Recruiting

Conditions: Drug Resistant Epilepsy

Interventions: Device: Focused ultrasound

First Posted Date: 2019-03-11

Last Posted Date: 2023-11-13

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 10

Registration Number: NCT03868293

Locations: 🇺🇸
Brigham and women's Hospital, Boston, Massachusetts, United States

The Functional Neuroanatomy of the Human Physiological Stress Response

Not Applicable

Recruiting

Conditions: Hypoglycemia
Physiological Stress

Interventions: Other: Hypoglycemic Hyperinsulinemic Clamp
Other: Normoglycemic Hyperinsulinemic Clamp

First Posted Date: 2019-03-08

Last Posted Date: 2023-07-27

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 44

Registration Number: NCT03867344

Locations: 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States

Tranexamic Acid Pharmacokinetics During Postpartum Hemorrhage

Early Phase 1

Completed

Conditions: Postpartum Hemorrhage

Interventions: Diagnostic Test: blood test

First Posted Date: 2019-03-05

Last Posted Date: 2021-04-13

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 20

Registration Number: NCT03863964

Locations: 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States

Pharmacological Activation of HMN for OSA Aim 2

Phase 1

Recruiting

Conditions: Obstructive Sleep Apnea

Interventions: Drug: LTM1201AD
Drug: Placebo oral capsule
Drug: LTM1201AZ
Drug: LTM1201AG
Drug: LTM1201AT

First Posted Date: 2019-03-01

Last Posted Date: 2022-09-21

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 16

Registration Number: NCT03858751

Locations: 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States

Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use

Phase 4

Completed

Conditions: Substance Use Disorders
HIV/AIDS
Adherence, Medication

Interventions: Device: Digital pill
Drug: Truvada

First Posted Date: 2019-02-15

Last Posted Date: 2022-12-22

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 16

Registration Number: NCT03842436

Locations: 🇺🇸
Fenway Health, Boylston, Massachusetts, United States

Assessing if Cryoneurolysis Improves Prehabilitation and Decreases Pain After Surgery With Less Opioid Use in TKA Patients

Not Applicable

Withdrawn

Conditions: Arthritis Knee
Pain, Joint
Opioid Use
Arthropathy of Knee

Interventions: Device: iovera°

First Posted Date: 2019-02-11

Last Posted Date: 2019-07-10

Lead Sponsor: Brigham and Women's Hospital

Registration Number: NCT03836313

The Impact of a Newborn Behavioral Intervention on the Mental Health of Mothers With Late Pre-Term Infants

Not Applicable

Completed

Conditions: Postpartum Depression
Infant Development
Preterm Infant

Interventions: Behavioral: Newborn Behavioral Observation-Family Wellness (NBO-FW)

First Posted Date: 2019-02-11

Last Posted Date: 2022-08-17

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 208

Registration Number: NCT03836430

Locations: 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States

ICON-2: FMT and Bezlotoxumab Compared to FMT and Placebo for Patients With IBD and CDI

Phase 2

Active, not recruiting

Conditions: Inflammatory Bowel Diseases
Clostridium Difficile Infection

Interventions: Drug: Bezlotoxumab
Drug: Placebo
Drug: Fecal Microbiota Transplantation

First Posted Date: 2019-02-04

Last Posted Date: 2024-12-11

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 61

Registration Number: NCT03829475

Locations: 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States

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