The European Commission granted NLX-112 (Neurolixis) orphan medicinal product designation for treating spinocerebellar ataxia (SCA), based on successful preclinical trials showing significant motor dysfunction reduction in SCA3 models. This designation offers 10 years of market exclusivity, with potential for an additional 2 years if a pediatric assessment plan is met. NLX-112, an oral serotonin 5-HT1A receptor agonist, has also shown efficacy in Parkinson's disease trials, reducing levodopa-induced dyskinesia and motor impairment.