Wall Street is bullish on Viking Therapeutics (VKTX) due to successful clinical trials of its weight loss drug VK2735, which showed significant weight loss in patients. Billionaires Jeff Yass and Israel Englander have increased their stakes in the company. VK2735, a dual GLP-1 and GIP receptor agonist, outperformed competitors like Novo Nordisk's semaglutide and Eli Lilly's tirzepatide. Viking Therapeutics also has a promising drug, VK2809, for metabolic dysfunction-associated steatohepatitis (MASH). Upcoming catalysts include phase 3 trials for VK2735 and a phase 2 study of oral VK2735. Despite potential risks, Viking Therapeutics is considered a high-risk, high-reward investment.