VA Office of Research and Development

Spinal Cord Injury Treatment Market Poised for Growth with Emerging Therapies

4 months ago

• The spinal cord injury (SCI) market is projected to grow significantly, driven by increasing prevalence and advancements in treatment options. • Emerging therapies like KP-100IT, Neuro-Cells, and MT-3921 are expected to transform the SCI treatment landscape, offering new standards of care. • Clinical trials are underway for several promising SCI treatments, including NervGen Pharma's NVG-291 and Mitsubishi Tanabe Pharma's MT-3921. • The SCI market in the 7MM is estimated to increase from USD 345 million in 2023 to a CAGR of 15.4% by 2034, according to DelveInsight.

Spinal Cord Injury and Ankylosing Spondylitis: Advances in Clinical Trials and Therapies

6 months ago

• Spinal Cord Injury (SCI) pipeline includes 35+ therapies from companies like Athersys and NervGen Pharma, targeting mechanisms from stem cell therapy to neuroprotection. • Ankylosing Spondylitis (AS) pipeline features 20+ therapies, with companies like UCB Biopharma and MoonLake Immunotherapeutics developing treatments such as bimekizumab and sonelokimab. • Clinical trials for SCI include Neuroplast's Phase II trial of Neuro-Cells® showing promising safety, while NeuroSolv Therapeutics seeks investment for Perineline™ to address SCI. • Recent data presented by UCB Biopharma at ACR 2024 highlights sustained improvements in AS with bimekizumab, and AbbVie's RINVOQ is prescribed for adults with active AS.

Acupuncture Shows Promise in Alleviating Combat-Related PTSD Symptoms in Veterans

4 years ago

• A randomized, placebo-controlled trial is underway to evaluate the clinical and biological effects of verum acupuncture for combat-related PTSD in US Veterans. • The study compares verum acupuncture to sham acupuncture, assessing changes in PTSD symptom severity and psychophysiological responses. • Researchers aim to address limitations of previous acupuncture trials by including a sham control, biological outcomes, and monitoring protocol adherence. • Expected results will offer definitive insights into acupuncture's efficacy, potentially influencing PTSD treatment approaches within and beyond the VA system.