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Alumis, Inc.

Alumis, Inc. logo
🇺🇸United States
Ownership
Public
Established
2021-01-01
Employees
11
Market Cap
$685.4M
Website
http://www.alumis.com

A Study in Patients with Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001

Phase 3
Recruiting
Conditions
Plaque Psoriasis
Interventions
Drug: ESK-001
Drug: Placebo
Drug: Apremilast
First Posted Date
2024-09-19
Last Posted Date
2024-12-20
Lead Sponsor
Alumis Inc
Target Recruit Count
840
Registration Number
NCT06588738
Locations
🇨🇦

CCA Medical Research Corp, Ajax, Ontario, Canada

🇨🇦

SKiN Health, Cobourg, Ontario, Canada

🇨🇦

Kingsway Clinical Research, Etobicoke, Ontario, Canada

and more 42 locations

A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients with Moderate to Severe Plaque Psoriasis

Phase 3
Recruiting
Conditions
Plaque Psoriasis
Interventions
Drug: ESK-001
Drug: Placebo
Drug: Apremilast
First Posted Date
2024-09-19
Last Posted Date
2024-12-27
Lead Sponsor
Alumis Inc
Target Recruit Count
840
Registration Number
NCT06586112
Locations
🇺🇸

MetroMed Clinical Trials, Chicago, Illinois, United States

🇺🇸

MetroBoston Clinical Partners, Brighton, Massachusetts, United States

🇺🇸

Cleaver Dermatology, Kirksville, Missouri, United States

and more 57 locations

Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus

Phase 2
Recruiting
Conditions
SLE
Interventions
Drug: ESK-001
Drug: Placebo
First Posted Date
2023-07-28
Last Posted Date
2025-01-07
Lead Sponsor
Alumis Inc
Target Recruit Count
388
Registration Number
NCT05966480
Locations
🇺🇸

Investigator Site #1189, Sparta, New Jersey, United States

🇺🇸

Investigator Site #1195, Carrollton, Texas, United States

🇺🇸

Investigator site #1178, Houston, Texas, United States

and more 171 locations

POC Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Active Intermediate, Posterior, or Pan NIU

Phase 2
Terminated
Conditions
Noninfectious Panuveitis
Uveitis Posterior Non-Infectious
Uveitis, Intermediate
Interventions
Drug: ESK-001
First Posted Date
2023-07-20
Last Posted Date
2024-08-28
Lead Sponsor
Alumis Inc
Target Recruit Count
36
Registration Number
NCT05953688
Locations
🇺🇸

Investigator Site #1076, Palisades Park, New Jersey, United States

🇺🇸

Investigator Site #1064, Erie, Pennsylvania, United States

🇺🇸

Investigator Site #1073, Los Angeles, California, United States

and more 14 locations

Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis

Phase 2
Active, not recruiting
Conditions
Plaque Psoriasis
Interventions
Drug: ESK-001
First Posted Date
2023-02-22
Last Posted Date
2024-05-13
Lead Sponsor
Alumis Inc
Target Recruit Count
165
Registration Number
NCT05739435
Locations
🇺🇸

Investigator Site #1018, Los Angeles, California, United States

🇺🇸

Investigator Site #1035, Macon, Georgia, United States

🇺🇸

Investigator Site #1017, Owensboro, Kentucky, United States

and more 35 locations

A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque Psoriasis

Phase 2
Completed
Conditions
Plaque Psoriasis
Interventions
Drug: ESK-001
Drug: Placebo
First Posted Date
2022-10-31
Last Posted Date
2024-07-23
Lead Sponsor
Alumis Inc
Target Recruit Count
228
Registration Number
NCT05600036
Locations
🇺🇸

Investigator Site #1035, Macon, Georgia, United States

🇺🇸

Investigator Site #1017, Owensboro, Kentucky, United States

🇺🇸

Investigator Site #1031, New Brighton, Minnesota, United States

and more 50 locations

Multiple Dose Study to Determine Safety and Tolerability of ESK-001 in Healthy Participants

Phase 1
Completed
Conditions
Safety and Tolerability
Interventions
Other: Placebo
First Posted Date
2022-06-24
Last Posted Date
2023-05-09
Lead Sponsor
Alumis Inc
Target Recruit Count
49
Registration Number
NCT05431634
Locations
🇺🇸

Alumis Central site, Glendale, California, United States

Relative Bioavailability of ESK-001 Tablet Versus Liquid in Healthy Participants

Phase 1
Completed
Conditions
Pharmacokinetics
Interventions
Drug: ESK-001
Drug: Rabeprazole
First Posted Date
2022-04-15
Last Posted Date
2023-05-09
Lead Sponsor
Alumis Inc
Target Recruit Count
14
Registration Number
NCT05330858
Locations
🇺🇸

Alumis Central Site, Glendale, California, United States

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