MedPath

Alumis, Inc.

Alumis, Inc. logo
🇺🇸United States
Ownership
Public
Established
2021-01-01
Employees
11
Market Cap
$685.4M
Website
http://www.alumis.com

Clinical Trials

19

Active:6
Completed:3

Trial Phases

3 Phases

Phase 1:7
Phase 2:7
Phase 3:4

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (18 trials with phase data)• Click on a phase to view related trials

Phase 1
7 (38.9%)
Phase 2
7 (38.9%)
Phase 3
4 (22.2%)

An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function

Phase 1
Recruiting
Conditions
Renal Impairment
Interventions
First Posted Date
2025-05-08
Last Posted Date
2025-05-08
Lead Sponsor
Alumis Inc
Target Recruit Count
48
Registration Number
NCT06962774
Locations
🇺🇸

Panax Clinical Research, Miami Lakes, Florida, United States

🇺🇸

Floridian Clinical Research, Miami Lakes, Florida, United States

🇺🇸

Advanced Pharma CR, Miami, Florida, United States

and more 1 locations

An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage

Phase 1
Recruiting
Conditions
Hepatic Impairment
Interventions
First Posted Date
2025-05-01
Last Posted Date
2025-05-01
Lead Sponsor
Alumis Inc
Target Recruit Count
48
Registration Number
NCT06952634
Locations
🇺🇸

Orange County Research Center, Lake Forest, California, United States

🇺🇸

Panax Clinical Research, Miami Lakes, Florida, United States

🇺🇸

Orlando Clinical Research Center, Orlando, Florida, United States

and more 1 locations

Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis

Phase 3
Recruiting
Conditions
Plaque Psoriasis
Psoriasis (PsO)
Psoriasis
Moderate Psoriasis
Severe Psoriasis
Interventions
Drug: Open-Label ESK-001
Drug: Blinded ESK-001
Drug: Placebo
First Posted Date
2025-02-26
Last Posted Date
2025-06-26
Lead Sponsor
Alumis Inc
Target Recruit Count
1680
Registration Number
NCT06846541
Locations
🇺🇸

Total Dermatology, Birmingham, Alabama, United States

🇺🇸

Chandler Clinical Trials, Chandler, Arizona, United States

🇺🇸

Alliance Dermatology, Pheonix, Arizona, United States

and more 81 locations

A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001

Phase 3
Active, not recruiting
Conditions
Plaque Psoriasis
Interventions
First Posted Date
2024-09-19
Last Posted Date
2025-06-20
Lead Sponsor
Alumis Inc
Target Recruit Count
840
Registration Number
NCT06588738
Locations
🇺🇸

Total Skin and Beauty Dermatology Center, PC, Birmingham, Alabama, United States

🇺🇸

Chandler Clinical Trials, Chandler, Arizona, United States

🇺🇸

Medical Dermatology Specialists, Phoenix, Arizona, United States

and more 145 locations

A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis

Phase 3
Active, not recruiting
Conditions
Plaque Psoriasis
Interventions
First Posted Date
2024-09-19
Last Posted Date
2025-06-20
Lead Sponsor
Alumis Inc
Target Recruit Count
840
Registration Number
NCT06586112
Locations
🇺🇸

Alliance Dermatology, Phoenix, Arizona, United States

🇺🇸

Scottsdale Clinical Trials, Scottsdale, Arizona, United States

🇺🇸

Northwest Arkansas Clinical Trials Center (NWACTC), PLLC, Rogers, Arkansas, United States

and more 180 locations
  • Prev
  • 1
  • 2
  • 3
  • Next

News

Robust Pipeline of 80+ Therapies Advancing in Psoriasis Treatment Landscape

DelveInsight's 2025 Psoriasis Pipeline Report reveals over 80 companies developing 80+ pipeline therapies, highlighting significant R&D investment in this therapeutic area.

Alumis to Present 52-Week Phase 2 Data for Novel TYK2 Inhibitor in Psoriasis at AAD 2025

Alumis will showcase long-term safety and efficacy data for ESK-001, their oral TYK2 inhibitor, in moderate-to-severe plaque psoriasis through multiple presentations at the 2025 AAD annual meeting.

© Copyright 2025. All Rights Reserved by MedPath