JOHN MUIR HEALTH

Oncology Workforce Crisis Drives Push for Enhanced Collaboration and Value-Based Care

3 months ago

• Experts project a 40% increase in cancer care demand amid growing oncologist shortages, emphasizing the critical need for streamlined collaboration between healthcare providers and payers. • Fred Hutchinson Cancer Center demonstrates success with multidisciplinary care model, expanding from 3 to 13 team members and implementing innovative outpatient-specific approaches to improve patient care delivery. • Healthcare leaders stress the importance of balancing clinical guidelines with personalized care while highlighting the potential of emerging treatments like TIL therapy in addressing complex cancer cases.

CAR T-cell Therapies Show Promise in Relapsed Multiple Myeloma

4 months ago

• Allogeneic BCMA CAR T-cell therapy demonstrates promising efficacy and reasonable safety in relapsed multiple myeloma, utilizing CRISPR technology to mitigate graft-versus-host disease. • A clinical trial targeting GPRC5D shows high efficacy in patients who have relapsed after BCMA-targeted therapy, potentially offering a more favorable treatment option. • The allogeneic approach allows for faster treatment delivery using "off-the-shelf" cells, addressing a key limitation of autologous CAR T-cell therapies. • Early results indicate high efficacy in minority patients, who are often underrepresented in clinical trials, highlighting the therapy's potential for broader impact.