A study evaluated the effectiveness of a Clinical Trial Matching System (CTMS) integrated with the Chinese Electronic Health Record (EHR) system for screening patients with hepatocellular carcinoma (HCC) for clinical trials. The CTMS, utilizing artificial intelligence (AI) technologies like natural language processing (NLP) and machine learning (ML), demonstrated high specificity and good sensitivity in matching patients to clinical trials, significantly reducing the time required for screening compared to manual methods.