Great Ormond Street Hospital for Children NHS Foundation Trust

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private

Employees: -

Market Cap: -

Website: http://www.gosh.nhs.uk

Clinical Trials

Identifying and Understanding Risk Factors for Instability and Adverse Events Associated With Chest Physiotherapy in Ventilated Children

Completed

Conditions: Respiratory Failure

First Posted Date: 2019-10-31

Last Posted Date: 2022-01-10

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 556

Registration Number: NCT04146753

Locations: 🇬🇧
Great Ormond Street Hospital, London, United Kingdom

Evaluation of Aid to Diagnosis for Congenital Dysplasia of the Hip in General Practice

Not Applicable

Active, not recruiting

Conditions: Developmental Dysplasia of the Hip

Interventions: Diagnostic Test: The 6-week Hip Checklist

First Posted Date: 2019-09-24

Last Posted Date: 2024-05-23

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 172

Registration Number: NCT04101903

Locations: 🇬🇧
Rise Group Practice, London, United Kingdom

Yttrium-90 Anti CD66 Monoclonal Antibody in Childhood Relapsed/Refractory Leukaemia

Phase 1

Completed

Conditions: Acute Lymphoblastic Leukemia
Juvenile Myelomonocytic Leukemia
Acute Myeloblastic Leukemia

Interventions: Other: Yttrium-90 labelled monoclonal antibody against CD66

First Posted Date: 2019-09-09

Last Posted Date: 2021-06-25

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 9

Registration Number: NCT04082286

Locations: 🇬🇧
Great Ormond Street Hospital for Children, London, United Kingdom

What is the Feasibility of the ISTEP Exercise Test in Boys With Haemophilia

Not Applicable

Completed

Conditions: Hemophilia

Interventions: Other: iSTEP exercise testing

First Posted Date: 2019-09-03

Last Posted Date: 2019-09-06

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 43

Registration Number: NCT04076306

Locations: 🇬🇧
Research and Development Office, Division of Research and Innovation,, London, United Kingdom

Novel Network Analysis of Intracranial Stereoelectroencephalography

Not Applicable

Conditions: Refractory Epilepsy
Epilepsy in Children
Epilepsies, Partial
Epilepsy Intractable
Intractable Epilepsy
Focal Epilepsy
Epilepsy, Focal

Interventions: Procedure: Combined Micro-Macro SEEG Electrodes

First Posted Date: 2019-04-16

Last Posted Date: 2021-11-19

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 20

Registration Number: NCT03916848

Locations: 🇬🇧
Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom

'Fitness To Fly' Tests In Children With Type II Respiratory Failure

Not Applicable

Completed

Conditions: Central Hypoventilation
Neuromuscular Diseases

Interventions: Diagnostic Test: Hypoxic challenge test

First Posted Date: 2019-01-31

Last Posted Date: 2021-12-08

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 20

Registration Number: NCT03824223

Locations: 🇬🇧
Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Phase 1

Completed

Conditions: Severe Combined Immunodeficiency Due to ADA Deficiency

Interventions: Genetic: Infusion of autologous cryopreserved EFS-ADA LV CD34+ cells (OTL-101)
Drug: Busulfan
Drug: Peg-Ada

First Posted Date: 2018-12-05

Last Posted Date: 2023-02-01

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 13

Registration Number: NCT03765632

Locations: 🇬🇧
Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom

Infant and Child European Cryoablation Project ICECaP

Recruiting

Conditions: Therapy
Cryoablation
Soft Tissue Lesion
Pediatric

Interventions: Procedure: Cryoablation

First Posted Date: 2018-10-26

Last Posted Date: 2024-10-26

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 40

Registration Number: NCT03721783

Locations: 🇬🇧
Great, London, United Kingdom

Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency

Phase 1

Recruiting

Conditions: Severe Combined Immunodeficiency, X-Linked

Interventions: Drug: Lentiviral vector transduced CD34+ cells

First Posted Date: 2018-07-26

Last Posted Date: 2023-10-12

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 5

Registration Number: NCT03601286

Locations: 🇬🇧
Great Ormond Street Hospital for Children NHS Foundation Trust, London, Greater London, United Kingdom

Differences in Access to Emergency Paediatric Intensive Care and Care During Transport

Completed

Conditions: Access and Transport to Paediatric Intensive Care

First Posted Date: 2018-05-09

Last Posted Date: 2022-10-04

Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Target Recruit Count: 2838

Registration Number: NCT03520192

Locations: 🇬🇧
Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom

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