University of Iowa

Novartis' oral Fabhalta® (iptacopan) sustained clinically meaningful results at one year in Phase III C3 glomerulopathy (C3G) trial, showing sustained proteinuria reduction and improved eGFR slope, with a favorable safety profile. Fabhalta is the only oral alternative complement pathway inhibitor targeting C3G's underlying cause, with regulatory submissions completed in the EU, China, and Japan, and expected in the US by year-end.

Novartis' oral Fabhalta® (iptacopan) sustained clinically meaningful results at one year in Phase III C3 glomerulopathy (C3G) trial, showing sustained proteinuria reduction, improved eGFR slope, and a favorable safety profile.

ASN Kidney Week 2024 will present high-impact phase 3 clinical trials on hyponatremia, pegcetacoplan, semaglutide, Pain Coping Skills Training, Humacyte's ATEV, and dapagliflozin, affecting kidney care.

23 carbon storage projects shortlisted for $518 million DOE support, aiming to store 50 million tons of CO2 annually. Key projects include West Virginia's $44 million hub and North Dakota's Project Tundra with $49 million.

Various projects aim to assess and establish the feasibility of commercial large-scale CO₂ storage complexes across the U.S., focusing on geological analysis, risk assessment, and community engagement to store over 50 million metric tons of CO₂.

Three Physics and Astronomy graduate students at the University of Iowa received scholarships. Michael Hite and Sarah Choate won the Ballard and Seashore Fellowship, each receiving $11,000 to focus on dissertation research. Hite models lattice gauge theories, while Choate measures neutrino magnetic moments. Dylan Blend was awarded the Graduate College Post-Comprehensive Research Fellowship, also receiving $11,000, and is involved in the CMS Outer Tracker Phase II Upgrade and DUNE experiment.

A case study from the NIH Pragmatic Trials Collaboratory describes an interim reassessment of sample size during an ongoing cluster randomized trial, FM-TIPS, which examines the effect of transcutaneous electrical nerve stimulation on movement-evoked pain in fibromyalgia patients.

The Arthritis Foundation awarded $150,000 each to Cara Lewis and Michael Willey/Jessica Goetz for FastOA research on hip OA risk in young female athletes and post-surgical hip dysplasia patients, respectively.

Iowa City Council voted 4-1 to ban kratom sales, with two members absent. The ban, if passed, would be the first in the area, limiting sales but not possession or use. Councilor Megan Alter opposed the ban, citing lack of comprehensive information and the legality of more harmful substances like cigarettes and alcohol.