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Myokardia, Inc.

Myokardia, Inc. logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
2012-09-01
Employees
251
Market Cap
-
Website
http://www.myokardia.com

Clinical Trials

59

Active:45
Completed:10

Trial Phases

3 Phases

Phase 1:49
Phase 2:3
Phase 3:7

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (59 trials with phase data)• Click on a phase to view related trials

Phase 1
49 (83.1%)
Phase 3
7 (11.9%)
Phase 2
3 (5.1%)

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Phase 3
Completed
Conditions
Obstructive Hypertrophic Cardiomyopathy
Interventions
Drug: Placebo
First Posted Date
2018-03-20
Last Posted Date
2021-10-04
Lead Sponsor
MyoKardia, Inc.
Target Recruit Count
251
Registration Number
NCT03470545
Locations
🇺🇸

Mayo Clinic Arizona, Scottsdale, Arizona, United States

🇺🇸

Cedars-Sinai Medical Center (Smidt Heart Institute), Los Angeles, California, United States

🇺🇸

UCSF School of Medicine, San Francisco, California, United States

and more 68 locations

A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

Phase 2
Completed
Conditions
Non-obstructive Hypertrophic Cardiomyopathy
Interventions
Drug: Placebo
First Posted Date
2018-02-22
Last Posted Date
2022-08-09
Lead Sponsor
MyoKardia, Inc.
Target Recruit Count
59
Registration Number
NCT03442764
Locations
🇺🇸

Mayo Clinic Arizona, Scottsdale, Arizona, United States

🇺🇸

Cedars-Sinai Medical Center (Smidt Heart Institute), Los Angeles, California, United States

🇺🇸

Stanford Hospital and Clinics/Stanford University, Palo Alto, California, United States

and more 29 locations

A Single Ascending Dose Study Assessing the Safety, Tolerability, PK and PD of MYK-491

Phase 1
Completed
Conditions
Dilated Cardiomyopathy
Interventions
Drug: MYK-491 or placebo
First Posted Date
2017-02-24
Last Posted Date
2018-03-23
Lead Sponsor
MyoKardia, Inc.
Target Recruit Count
64
Registration Number
NCT03062956
Locations
🇦🇺

Nucleus Network, Melbourne, Victoria, Australia

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

Phase 2
Completed
Conditions
Left Ventricular Outflow Tract Obstruction
Cardiomyopathy, Hypertrophic Obstructive
Interventions
First Posted Date
2016-07-22
Last Posted Date
2021-06-08
Lead Sponsor
MyoKardia, Inc.
Target Recruit Count
21
Registration Number
NCT02842242
Locations
🇺🇸

Mayo Clinic Arizona, Scottsdale, Arizona, United States

🇺🇸

Yale New Haven Hospital, New Haven, Connecticut, United States

🇺🇸

Tufts Medical Center, Boston, Massachusetts, United States

and more 4 locations

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Oral Doses of MYK-461 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
First Posted Date
2015-06-24
Last Posted Date
2017-03-22
Lead Sponsor
MyoKardia, Inc.
Target Recruit Count
60
Registration Number
NCT02480296
Locations
🇦🇺

Nucleus Network, Melbourne, Victoria, Australia

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