Fudan University

Kynurenine, a tryptophan metabolite, exacerbates Alzheimer’s disease (AD) by inhibiting astrocyte glycolysis and lactate production, starving neurons. IDO1 inhibitors, which block kynurenine production, could potentially treat AD and other neurodegenerative diseases.

UltraDx Bio's UD-X™ Single-Molecule Analyzer received China's first clinical registration approval, revolutionizing early screening for Alzheimer's Disease. The analyzer, listed on the National Medical Products Administration website, detects trace protein biomarkers at the fg/ml scale, addressing precision detection needs in clinical diagnostics.