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Longboard Pharmaceuticals

Longboard Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Employees
50
Market Cap
$1.3B
Website
http://www.longboardpharma.com
Introduction

Longboard Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company, which engages in the research and development of medicines for neurological diseases. The company was founded on January 3, 2020 and is headquartered in San Diego, CA.

Clinical Trials

6

Active:0
Completed:2

Trial Phases

3 Phases

Phase 1:1
Phase 2:1
Phase 3:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (5 trials with phase data)• Click on a phase to view related trials

Phase 3
3 (60.0%)
Phase 1
1 (20.0%)
Phase 2
1 (20.0%)

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)

Phase 3
Conditions
Developmental and Epileptic Encephalopathy
Interventions
First Posted Date
2025-04-03
Last Posted Date
2025-07-11
Lead Sponsor
Longboard Pharmaceuticals
Target Recruit Count
324
Registration Number
NCT06908226
Locations
🇺🇸

Site Number - USA19, Little Rock, Arkansas, United States

🇺🇸

Site Number - USA29, La Jolla, California, United States

🇺🇸

Site Number - USA26, Los Angeles, California, United States

and more 30 locations

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

Phase 3
Recruiting
Conditions
Developmental and Epileptic Encephalopathy
Interventions
Drug: Placebo
First Posted Date
2024-12-05
Last Posted Date
2025-07-11
Lead Sponsor
Longboard Pharmaceuticals
Target Recruit Count
320
Registration Number
NCT06719141
Locations
🇺🇸

Site Number - USA19, Little Rock, Arkansas, United States

🇺🇸

Site Number - USA29, La Jolla, California, United States

🇺🇸

Site Number - USA26, Los Angeles, California, United States

and more 96 locations

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

Phase 3
Recruiting
Conditions
Dravet Syndrome
Interventions
Drug: Placebo
First Posted Date
2024-10-28
Last Posted Date
2025-07-11
Lead Sponsor
Longboard Pharmaceuticals
Target Recruit Count
160
Registration Number
NCT06660394
Locations
🇺🇸

Site Number - USA19, Little Rock, Arkansas, United States

🇺🇸

Site Number - USA29, La Jolla, California, United States

🇺🇸

Site Number - USA26, Los Angeles, California, United States

and more 89 locations

Intermediate-Size Expanded Access Protocol (EAP) for LP352

Conditions
Dravet Syndrome
Lennox Gastaut Syndrome
Developmental and Epileptic Encephalopathies
First Posted Date
2023-11-29
Last Posted Date
2025-01-22
Lead Sponsor
Longboard Pharmaceuticals
Registration Number
NCT06149663
Locations
🇺🇸

Rancho Research Institute, Downey, California, United States

🇺🇸

University of California Los Angeles (UCLA), Los Angeles, California, United States

🇺🇸

University of California Benioff Childrens Hospital, San Francisco, California, United States

and more 19 locations

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Phase 2
Completed
Conditions
Lennox-Gastaut Syndrome
Dravet Syndrome
Developmental and Epileptic Encephalopathy
Interventions
Drug: LP352, bexicaserin
First Posted Date
2022-11-25
Last Posted Date
2025-01-27
Lead Sponsor
Longboard Pharmaceuticals
Target Recruit Count
41
Registration Number
NCT05626634
Locations
🇺🇸

Arkansas Children's Hospital, Little Rock, Arkansas, United States

🇺🇸

Rancho Los Amigos National Rehabilitation Center (RLANRC), Downey, California, United States

🇺🇸

University of California San Francisco, San Francisco, California, United States

and more 25 locations
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News

Global Clinical Trials for Dravet Syndrome Reviewed in 2024

• A new report offers an overview of the clinical trial landscape for Dravet Syndrome, also known as Severe Myoclonic Epilepsy of Infancy, providing key data and analysis. • The review includes data on trial numbers, average enrollment, and top countries involved, segmented by region, phase, status, endpoints, and sponsor type. • Key companies like Jazz Pharmaceuticals, UCB, Takeda, and others are profiled, with details on their ongoing trials and prominent drugs in development for Dravet Syndrome. • The report identifies trends in clinical trial enrollment over the past five years and highlights recent news related to Dravet Syndrome research and development.

Bexicaserin Shows Sustained Seizure Reduction in Developmental Epileptic Encephalopathies

Bexicaserin demonstrated a 59.3% median reduction in countable motor seizures over 12 months in patients with developmental and epileptic encephalopathies (DEEs).

Longboard Pharmaceuticals Initiates Phase III Trial of Bexicaserin for Developmental and Epileptic Encephalopathies

Longboard Pharmaceuticals has commenced the Phase III DEEp OCEAN study to evaluate bexicaserin for seizures associated with developmental and epileptic encephalopathies (DEEs).

Longboard Pharmaceuticals Launches Phase 3 Trial of Bexicaserin for Developmental and Epileptic Encephalopathies

Longboard Pharmaceuticals has initiated the Phase 3 DEEp OCEAN study to evaluate bexicaserin for seizures associated with Developmental and Epileptic Encephalopathies (DEEs).

Longboard Pharmaceuticals Advances Bexicaserin for Dravet Syndrome

Longboard Pharmaceuticals initiated a Phase 3 clinical trial, DEEp SEA, to evaluate bexicaserin in Dravet syndrome patients aged 2-65 years.

Longboard Pharmaceuticals Initiates Phase 3 Trial of Bexicaserin for Dravet Syndrome

Longboard Pharmaceuticals has started a Phase 3 clinical trial, DEEp SEA, to assess bexicaserin in Dravet syndrome patients aged 2-65 years.

Epilepsy Pipeline Shows Promise with Novel Therapies in Clinical Trials

Over 90 epilepsy treatment therapies are under development by more than 75 companies globally, targeting various mechanisms of action and routes of administration.

Lundbeck to Acquire Longboard Pharmaceuticals for $2.6 Billion, Bolstering Epilepsy Pipeline

Lundbeck will acquire Longboard Pharmaceuticals for $2.6 billion, gaining bexicaserin, a promising drug for developmental and epileptic encephalopathies (DEEs).

Lundbeck to Acquire Longboard Pharmaceuticals for $2.6 Billion, Bolstering Dravet Syndrome Pipeline

Lundbeck announces a definitive agreement to acquire Longboard Pharmaceuticals for $2.6 billion in cash, expanding its neuroscience portfolio.

Longboard Pharmaceuticals Launches Phase 3 Trial of Bexicaserin for Dravet Syndrome

Longboard Pharmaceuticals has initiated a global Phase 3 trial, DEEp SEA, to evaluate bexicaserin for treating seizures associated with Dravet syndrome.

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