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KYMERA THERAPEUTICS INC

KYMERA THERAPEUTICS INC logo
🇺🇸United States
Ownership
Public
Established
2017-01-01
Employees
187
Market Cap
$3.1B
Website
http://www.kymeratx.com

First-in-human Study of Orally Administered KT-621 in Healthy Adult Participants

Phase 1
Recruiting
Conditions
Healthy Participants Study
Interventions
Drug: KT-621
Drug: Placebo
First Posted Date
2024-11-05
Last Posted Date
2024-11-05
Lead Sponsor
Kymera Therapeutics, Inc.
Target Recruit Count
120
Registration Number
NCT06673667
Locations
🇺🇸

Celerion, Lincoln, Nebraska, United States

Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors

Phase 1
Active, not recruiting
Conditions
Acute Lymphocytic Leukemia
Myeloid Malignancies
Lymphomas
Advanced Solid Tumors
Interventions
First Posted Date
2023-03-20
Last Posted Date
2024-11-04
Lead Sponsor
Kymera Therapeutics, Inc.
Target Recruit Count
70
Registration Number
NCT05775406
Locations
🇺🇸

HonorHealth Research Institute, Scottsdale, Arizona, United States

🇺🇸

University of California, Davis Comprehensive Cancer Center, Sacramento, California, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

and more 8 locations

Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL

Phase 1
Completed
Conditions
Diffuse Large B Cell Lymphoma
DLBCL
MYD88 Gene Mutation
Non Hodgkin Lymphoma
Interventions
Drug: KT-413
First Posted Date
2022-02-10
Last Posted Date
2024-12-10
Lead Sponsor
Kymera Therapeutics, Inc.
Target Recruit Count
7
Registration Number
NCT05233033
Locations
🇺🇸

MedStar Georgetown University Hospital, Washington, D.C., District of Columbia, United States

🇺🇸

Norton Cancer Institute, Louisville, Kentucky, United States

🇺🇸

Henry Ford Health System, Detroit, Michigan, United States

and more 5 locations

Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients with Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors

Phase 1
Active, not recruiting
Conditions
Non Hodgkin Lymphoma (NHL)
T-cell Prolymphocytic Leukemia (T-PLL)
Peripheral T-cell Lymphoma (PTCL)
Cutaneous T-Cell Lymphoma (CTCL)
Large Granular Lymphocytic Leukemia (LGL-L)
Solid Tumors
Interventions
First Posted Date
2022-02-04
Last Posted Date
2024-11-04
Lead Sponsor
Kymera Therapeutics, Inc.
Target Recruit Count
120
Registration Number
NCT05225584
Locations
🇺🇸

UC Irvine Health-Chao Family Comprehensive Cancer Center, Orange, California, United States

🇺🇸

Norton Cancer Institute, Louisville, Kentucky, United States

🇺🇸

Henry Ford Hospital, Detroit, Michigan, United States

and more 10 locations

A Single and Multiple Ascending Dose Trial of KT-474 in Healthy Adult Volunteers and Patients With Atopic Dermatitis (AD) or Hidradenitis Suppurativa (HS)

Phase 1
Completed
Conditions
Healthy Volunteer
Atopic Dermatitis
Hidradenitis Suppurativa
Interventions
Drug: KT-474/Placebo
Drug: KT-474
First Posted Date
2021-02-26
Last Posted Date
2022-10-24
Lead Sponsor
Kymera Therapeutics, Inc.
Target Recruit Count
154
Registration Number
NCT04772885
Locations
🇺🇸

Medical Dermatology Specialists, Phoenix, Arizona, United States

🇺🇸

Southwest Skin Specialists 32nd St, Phoenix, Arizona, United States

🇺🇸

Research Centers of America, Hollywood, Florida, United States

and more 11 locations

Evaluation of Cutaneous and Circulating Inflammatory Biomarkers in Hidradenitis Suppurativa and Atopic Dermatitis

Completed
Conditions
Dermatitis, Atopic
Hidradenitis Suppurativa
First Posted Date
2020-06-19
Last Posted Date
2021-04-13
Lead Sponsor
Kymera Therapeutics, Inc.
Target Recruit Count
40
Registration Number
NCT04440410
Locations
🇨🇦

York Dermatology Clinic and Research Centre, Richmond Hill, Ontario, Canada

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