Sparc Group LLC

Albumin-based delivery systems are pivotal in diagnostics and therapy, leveraging albumin's interaction with FcRn and gp60 receptors for targeted drug delivery and imaging. These systems benefit from albumin's prolonged circulation, tumor accumulation, and functionalization capabilities. Despite challenges like protein corona formation and the need for toxic cross-linking agents, albumin's versatility in drug delivery, especially in cancer therapy, is underscored by its ability to be modified for enhanced pharmacokinetics and targeted delivery. Research continues to explore albumin's role in improving therapeutic efficacy and diagnostic precision, with ongoing studies addressing its limitations and optimizing its applications in medical imaging and treatment.