• AmMax Bio has dosed the first patient in a Phase 2a study evaluating AMB-066 for colorectal cancer minimal residual disease (CRC MRD).
• The trial, led by Dr. Van K. Morris at MD Anderson Cancer Center, aims to address the unmet need for approved therapies for CRC MRD.
• AMB-066, a monoclonal antibody targeting CSF1R, has shown promise in preclinical data and a safety database of approximately 200 individuals.
• Approximately 20,000 patients are diagnosed annually in the U.S. with CRC MRD, which currently has no approved therapies beyond observation.