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BRISTOL MYERS SQUIBB

🇺🇸United States
Ownership
-
Established
1989-01-01
Employees
30K
Market Cap
$97.5B
Website
https://www.bms.com/

Clinical Trials

1.7k

Active:131
Completed:1202

Trial Phases

6 Phases

Early Phase 1:1
Phase 1:574
Phase 2:352
+3 more phases

Drug Approvals

11

SFDA:10
CIMA_AEMPS:1

Drug Approvals

REVIA COMPRIMIDOS RECUBIERTOS

Approval Date
Jul 14, 2025
CIMA_AEMPS

Clinical Trials

Distribution across different clinical trial phases (1336 trials with phase data)• Click on a phase to view related trials

Phase 1
574 (43.0%)
Phase 2
352 (26.3%)
Phase 3
320 (24.0%)
Phase 4
53 (4.0%)
Not Applicable
33 (2.5%)
phase_1_2
2 (0.1%)
Early Phase 1
1 (0.1%)
phase_2_3
1 (0.1%)

Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

Not Applicable
Not yet recruiting
Conditions
Plaque Psoriasis
Interventions
First Posted Date
2025-08-12
Last Posted Date
2025-08-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
3040
Registration Number
NCT07116967
Locations
🇺🇸

Local Institution - 0088, Birmingham, Alabama, United States

🇺🇸

Local Institution - 0107, Phoenix, Arizona, United States

🇺🇸

Local Institution - 0322, Scottsdale, Arizona, United States

and more 238 locations

A Study to Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the US

Active, not recruiting
Conditions
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Interventions
First Posted Date
2025-08-06
Last Posted Date
2025-08-06
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
150
Registration Number
NCT07107373
Locations
🇺🇸

University of California, San Francisco (UCSF), San Francisco, California, United States

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

Not Applicable
Not yet recruiting
Conditions
Urothelial Cancer
Interventions
First Posted Date
2025-08-06
Last Posted Date
2025-08-06
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
470
Registration Number
NCT07106762
Locations
🇺🇸

Local Institution - 0167, Gilbert, Arizona, United States

🇺🇸

Local Institution - 0162, Fullerton, California, United States

🇺🇸

Local Institution - 0163, Sacramento, California, United States

and more 87 locations

Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

Not yet recruiting
Conditions
Schizophrenia
Interventions
Drug: xanomeline and trospium chloride (XT) therapy
Drug: xanomeline and trospium chloride (X/T) therapy
First Posted Date
2025-08-03
Last Posted Date
2025-08-20
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
300
Registration Number
NCT07101094
Locations
🇺🇸

Local Institution - 0003, Evanston, Illinois, United States

🇺🇸

Local Institution - 0007, Baltimore, Maryland, United States

🇺🇸

Local Institution - 0004, Catonsville, Maryland, United States

and more 5 locations

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Not Applicable
Not yet recruiting
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2025-08-03
Last Posted Date
2025-08-19
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
596
Registration Number
NCT07100080
Locations
🇺🇸

Local Institution - 0154, Orange, California, United States

🇺🇸

Local Institution - 0139, Edwards, Colorado, United States

🇺🇸

Local Institution - 0085, Gainesville, Florida, United States

and more 150 locations
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News

I-Mab Strengthens Leadership Team with Three New Board Appointments and R&D Committee Formation

I-Mab appointed three seasoned biotech executives to key leadership positions, including Dr. Robert Lenz and Ms. Xin Liu to the Board of Directors and Dr. Ken Takeshita to the Scientific Advisory Board.

Bristol Myers Squibb to Present New Cardiovascular Data at ESC Congress 2025, Including Breakthrough Non-Obstructive HCM Trial Results

Bristol Myers Squibb will present new clinical and real-world data for Camzyos (mavacamten) and Eliquis (apixaban) at the European Society of Cardiology Congress 2025 in Madrid.

Agilent's MMR IHC Panel PharmDx Receives FDA Approval as Companion Diagnostic for Colorectal Cancer Immunotherapy

Agilent Technologies received FDA approval for its MMR IHC Panel pharmDx (Dako Omnis) as a companion diagnostic test to identify mismatch repair deficient colorectal cancer patients eligible for Bristol Myers Squibb's Opdivo immunotherapy treatments.

FDA Grants Breakthrough Therapy Designation to Bristol Myers Squibb and SystImmune's Iza-bren for Advanced EGFR-Mutant Lung Cancer

The FDA has granted breakthrough therapy designation to iza-bren, a first-in-class bispecific antibody-drug conjugate developed by Bristol Myers Squibb and SystImmune for treating advanced EGFR-mutant lung cancer.

Bristol-Myers Squibb, Exelixis, and Novartis Advance Pan-Tumor Rollover Study for Long-Term Nivolumab Safety Assessment

Bristol-Myers Squibb, Exelixis, and Novartis are collaborating on the Pan-Tumor Rollover Study to evaluate the long-term safety of nivolumab monotherapy and its combinations across various tumor types.

Repare Therapeutics Reports 52% Reduction in Q2 Loss Amid Strategic Pivot to Licensing Model

Repare Therapeutics narrowed its Q2 2025 GAAP loss per share to $0.39, significantly beating analyst estimates of -$0.56, primarily driven by a $5.7 million gain from technology platform licensing deals.

X4 Pharmaceuticals Secures $60 Million Financing and Installs New Leadership Team

X4 Pharmaceuticals announced a $60 million private placement financing led by Coastlands Capital, Bain Capital Life Sciences, and New Enterprise Associates to support continued development of mavorixafor.

IO Biotech's Melanoma Vaccine Narrowly Misses Primary Endpoint in Phase 3 Trial Despite Promising Subgroup Results

IO Biotech's cancer vaccine Cylembio combined with Keytruda showed a 23% relative risk reduction in disease progression or death compared to Keytruda alone, but narrowly missed statistical significance with a p-value of 0.056.

GSK's TIM-3 Inhibitor Cobolimab Fails Phase III Trial in Advanced Lung Cancer

GSK's anti-TIM-3 monoclonal antibody cobolimab failed to improve overall survival in the Phase III COSTAR trial for advanced non-small cell lung cancer patients previously treated with immunotherapy.

Bristol Myers Squibb and Bain Capital Launch $300M Immunology Drug Development Venture

Bristol Myers Squibb and Bain Capital have formed an independent company backed by $300 million to develop five experimental immunology drugs licensed from Bristol Myers.

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