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BRISTOL MYERS SQUIBB

🇺🇸United States
Ownership
-
Established
1989-01-01
Employees
30K
Market Cap
$97.5B
Website
https://www.bms.com/

A Study to Evaluate the Drug Levels of Deucravacitinib From Tablets After Oral Administration in Healthy Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2021-07-02
Last Posted Date
2022-03-11
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
61
Registration Number
NCT04949269
Locations
🇺🇸

Quotient Sciences Miami, Miami, Florida, United States

🇺🇸

PPD Development, LP, Austin, Texas, United States

A Study of BMS-986416 With and Without Nivolumab in Select Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2021-06-29
Last Posted Date
2025-04-09
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
67
Registration Number
NCT04943900
Locations
🇺🇸

Local Institution - 0006, Atlanta, Georgia, United States

🇺🇸

Local Institution - 0005, Baltimore, Maryland, United States

🇺🇸

Local Institution - 0002, Hackensack, New Jersey, United States

and more 16 locations

A Study to Determine the Effect of Famotidine on the Drug Levels of BMS-986256 in Healthy Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2021-06-28
Last Posted Date
2022-01-21
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
22
Registration Number
NCT04941755
Locations
🇺🇸

PPD Development, LP, Austin, Texas, United States

A Study of Participants With Squamous Cell Oesophageal Carcinoma Receiving Nivolumab as Part of an Early Access to Medicines Scheme (EAMS) Program in the United Kingdom

Completed
Conditions
Esophageal Squamous Cell Carcinoma
Interventions
Biological: Nivolumab
First Posted Date
2021-06-23
Last Posted Date
2022-05-25
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
87
Registration Number
NCT04936399
Locations
🇬🇧

Local Institution - 0037, Bristol, United Kingdom

🇬🇧

Local Institution, Walsall, United Kingdom

🇬🇧

Local Institution - 0006, Truro, Cornwall, United Kingdom

A Study to Characterize the Drug Levels of an Oral Contraceptive With and Without BMS-986166 in Healthy Female Participants of Childbearing Potential

Phase 1
Completed
Conditions
Healthy Participants
Interventions
Drug: Oral contraceptive
First Posted Date
2021-06-22
Last Posted Date
2022-03-18
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
25
Registration Number
NCT04934696
Locations
🇺🇸

West Coast Clinical Trials Global, Cypress, California, United States

A Study to Assess the Safety, Tolerability and Drug Levels of BMS-986172 in Healthy and Obese Participants, Including an Assessment of the Effects of Food on BMS-986172 Absorption

Phase 1
Completed
Conditions
Healthy Participants
Interventions
Other: Placebo
First Posted Date
2021-06-14
Last Posted Date
2022-06-06
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
40
Registration Number
NCT04926051
Locations
🇺🇸

ICON Plc (Legacy PRA), Lenexa, Kansas, United States

A Study to Compare the Response to Treatment With Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive, and Shared Epitope-positive Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Phase 3
Active, not recruiting
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2021-06-02
Last Posted Date
2025-02-19
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
338
Registration Number
NCT04909801
Locations
🇮🇹

Local Institution - 0078, Perugia, Italy

🇺🇸

Local Institution - 0036, Fullerton, California, United States

🇺🇸

Local Institution - 0086, Los Alamitos, California, United States

and more 72 locations

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs

Phase 3
Active, not recruiting
Conditions
Psoriatic Arthritis
Interventions
Other: Placebo
First Posted Date
2021-06-01
Last Posted Date
2024-05-31
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
650
Registration Number
NCT04908202
Locations
🇨🇳

Local Institution - 0122, Tainan, Taiwan

🇨🇳

Local Institution - 0120, Taipei City, Taiwan

🇨🇳

Local Institution - 0124, Taoyuan, Taiwan

and more 178 locations

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment

Phase 3
Active, not recruiting
Conditions
Psoriatic Arthritis
Interventions
First Posted Date
2021-06-01
Last Posted Date
2025-04-13
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
729
Registration Number
NCT04908189
Locations
🇨🇳

Local Institution - 0140, Pingxiang, Jiangxi, China

🇨🇳

Local Institution - 0191, Shenyang, Liaoning, China

🇨🇳

Local Institution - 0158, Baotou, Neimeng, China

and more 144 locations

A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors

Phase 1
Recruiting
Conditions
Gastric/Gastroesophageal Junction Adenocarcinoma
Carcinoma, Renal Cell
Cervical Cancer
Non-Small-Cell Lung Cancer
Urothelial Carcinoma
Ovarian Neoplasms
Microsatellite Stable Colorectal Cancer
Squamous Cell Carcinoma of Head and Neck
Triple Negative Breast Neoplasms
Pancreatic Adenocarcinoma
Interventions
First Posted Date
2021-05-20
Last Posted Date
2025-01-06
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
905
Registration Number
NCT04895709
Locations
🇩🇪

Universitaetsklinikum Essen, Essen, Germany

🇺🇸

Community Cancer Institute, Clovis, California, United States

🇺🇸

USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States

and more 44 locations
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