The FDA granted fast track designation to LP-184 for treating glioblastoma (GBM). LP-184, a small-molecule alkylating agent causing tumor cell death via DNA damage, is under investigation in a phase 1a trial (NCT05933265) to assess its safety, tolerability, and maximum tolerated dose (MTD) in patients with solid tumors, including GBM. Once the MTD is determined, Lantern Pharma plans to advance LP-184 as STAR-001 for GBM and other CNS cancers.