Carlisle Cos., Inc. engages in the design, manufacture, and distribution of building envelope products and energy solutions. It operates through the Carlisle Construction Materials (CCM) and Carlisle Weatherproofing Technologies (CWT) segments. The CCM segment produces single-ply roofing products and warranted roof systems and accessories for the commercial building industry, including ethylene propylene diene monomer (“EPDM”), thermoplastic polyolefin (“TPO”) and polyvinyl chloride (“PVC”) membrane, polyiso insulation, and engineered metal roofing and wall panel systems for commercial and residential buildings. The CWT segment produces spray polyurethane foam technologies, architectural metal, heating, ventilation and air conditioning (HVAC) hardware and sealants, below-grade waterproofing, and air and vapor barrier systems focused on the weatherproofing and thermal performance of the building envelope. The company was founded by Charles S. Moomy in 1917 and is headquartered in Scottsdale, AZ.
CSL and Arcturus Therapeutics achieve a breakthrough as KOSTAIVE becomes the first self-amplifying mRNA COVID-19 vaccine approved by the European Commission for adults 18 and older.
Australian regulators have approved Andembry, a novel engineered antibody treatment developed by CSL in Melbourne, offering new hope for hereditary angioedema patients.
The European Commission and the MHRA have approved CSL's Andembry (garadacimab) for preventing hereditary angioedema (HAE) attacks in patients aged 12 and older.
The Phase 3 IMAGINE trial, the largest placebo-controlled study in kidney transplant recipients with chronic active antibody-mediated rejection (caAMR), did not meet its primary efficacy outcome.
A Phase 3 trial (IMAGINE) evaluating clazakizumab for chronic active antibody-mediated rejection (caAMR) in kidney transplant recipients was terminated early due to futility.
Arcturus Therapeutics and CSL's self-amplifying mRNA vaccine, ARCT-154, demonstrates superior immune responses compared to BioNTech/Pfizer's Comirnaty vaccine after 12 months.
Japan's MHLW has approved Kostaive, a self-amplifying mRNA (sa-mRNA) COVID-19 vaccine developed by CSL and Arcturus Therapeutics, targeting the JN.1 Omicron subvariant.
Japan's MHLW has approved CSL and Arcturus Therapeutics' updated self-amplifying mRNA (sa-mRNA) COVID-19 vaccine, KOSTAIVE®, for adults 18 and older.
Researchers are exploring treatments for lipoprotein(a), a genetically influenced cholesterol type unaffected by statins, with therapies showing potential in early trials.
Arcturus Therapeutics is on track to deliver initial 4 million doses of Kostaive® in Q3, with European approval decision expected in the same quarter.