MEDICAL COLLEGE OF WISCONSIN

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1893-01-01

Employees: 5K

Market Cap: -

Website: http://www.mcw.edu

Clinical Trials

Percutaneous Neurostimulation to Treat Paroxysmal Sympathetic Hyperactivity in Children

Not Applicable

Recruiting

Conditions: Paroxysmal Sympathetic Hyperactivity

Interventions: Device: Percutaneous Electrical Nerve Field Stimulation (PENFS) device application

First Posted Date: 2022-04-25

Last Posted Date: 2024-12-05

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 20

Registration Number: NCT05343988

Locations: 🇺🇸
Children's Wisconsin, Milwaukee, Wisconsin, United States

CPI-613 (Devimistat) in Combination With Chemoradiation in Patients With Pancreatic Adenocarcinoma

Phase 1

Recruiting

Conditions: Pancreas Adenocarcinoma

Interventions: Drug: CPI-613® (Dose level 3.0 1,500 mg/m^2)
Drug: CPI-613® (Dose level -1.0 250 mg/m^2)
Drug: CPI-613® (Dose level 1.0 500 mg/m^2)
Drug: Gemcitabine
Drug: CPI-613® (Dose level 2.0 1,000 mg/m^2)
Radiation: Intensity-modulated Radiation Therapy
Drug: CPI-613® Maximum Tolerated Dose (MTD)

First Posted Date: 2022-04-13

Last Posted Date: 2024-07-29

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 24

Registration Number: NCT05325281

Locations: 🇺🇸
Froedtert & the Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Venetoclax to Augment Epigenetic Modification and Chemotherapy

Phase 1

Recruiting

Conditions: Acute Myeloid Leukemia Refractory
Acute Myeloid Leukemia, in Relapse

Interventions: Drug: Venetoclax
Drug: Azacitadine
Drug: Vorinostat
Drug: Cytarabine
Drug: Fludarabine
Drug: Filgrastim

First Posted Date: 2022-04-07

Last Posted Date: 2024-11-26

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 40

Registration Number: NCT05317403

Locations: 🇺🇸
Children's Wisconsin, Milwaukee, Wisconsin, United States

High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis

Not Applicable

Recruiting

Conditions: Solid Tumor

Interventions: Radiation: Re-irradiation

First Posted Date: 2022-03-29

Last Posted Date: 2024-05-21

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 120

Registration Number: NCT05301101

Locations: 🇺🇸
Froedtert Hospital, Milwaukee, Wisconsin, United States

Vascular Aging and Lp299v Study

Not Applicable

Recruiting

Conditions: Vascular Aging

Interventions: Other: Heat-Killed Placebo control fermented drink
Other: Lactobacillus Plantarum 299v in fermented oat drink

First Posted Date: 2022-03-25

Last Posted Date: 2024-03-12

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 20

Registration Number: NCT05296395

Locations: 🇺🇸
Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Loncastuximab Tesirine in Combination With DA-EPOCH-R in Patients With Previously Untreated Aggressive B-cell Lymphoid Malignancies

Phase 1

Recruiting

Conditions: B-cell Lymphoma
Burkitt Lymphoma

Interventions: Drug: Etoposide
Drug: Doxorubicin
Drug: Cyclophosphamide
Drug: Rituximab
Drug: Vincristine
Drug: Prednisone
Drug: Loncastuximab Tesirine 0.075 mg/kg by IV
Drug: Loncastuximab tesirine 0.12 mg/kg by IV
Drug: Loncastuximab tesirine 0.15 mg/kg by IV

First Posted Date: 2022-03-08

Last Posted Date: 2024-06-04

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 33

Registration Number: NCT05270057

Locations: 🇺🇸
University of Texas Southwestern, Dallas, Texas, United States
🇺🇸
University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States
🇺🇸
Froedtert Hospital & the Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Landmark vs. Ultrasound-Assisted Bone Marrow Biopsy Procedure Study

Not Applicable

Recruiting

Conditions: Bone Marrow Biopsy Procedure

Interventions: Procedure: Landmark palpation bone marrow biopsy
Device: Ultrasound-assisted bone marrow biopsy

First Posted Date: 2022-02-28

Last Posted Date: 2024-08-28

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 100

Registration Number: NCT05258357

Locations: 🇺🇸
Froedtert Hospital, Milwaukee, Wisconsin, United States

Impact of Lp299v on Vascular Function in Patients With PASC

Not Applicable

Recruiting

Conditions: COVID-19

Interventions: Other: Lactobacillus Plantarum 299v Freeze Dried Capsule
Other: Freeze Dried Potato Starch Capsule

First Posted Date: 2022-02-07

Last Posted Date: 2024-03-12

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 80

Registration Number: NCT05227170

Locations: 🇺🇸
Medical College of Wisconsin, Milwaukee, Wisconsin, United States

A Pilot Study of Reducing Test-Anxiety in a Cohort of Underrepresented in Medicine MCAT Students Using Near-Peer Coaching

Completed

Conditions: Test Anxiety

First Posted Date: 2022-02-04

Last Posted Date: 2023-06-28

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 22

Registration Number: NCT05224427

Locations: 🇺🇸
Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Understanding and Addressing Disparities in Cancer Therapy Induced Inflammation and Associated Endothelial Dysfunction

Not Applicable

Recruiting

Conditions: Breast Cancer

Interventions: Behavioral: Taking Charge during Treatment (TCT) Intervention

First Posted Date: 2022-02-03

Last Posted Date: 2024-04-30

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 80

Registration Number: NCT05223322

Locations: 🇺🇸
Medical College of Wisconsin, Wauwatosa, Wisconsin, United States
🇺🇸
University of Illinois Chicago, Chicago, Illinois, United States

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