ALEXION PHARMACEUTICALS, INC.

ALEXION PHARMACEUTICALS, INC. logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
1992-01-01
Employees
3.8K
Market Cap
-
Website
http://www.alexion.com

Prevention of Delayed Graft Function Using Eculizumab Therapy (PROTECT Study)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2014-05-22
Last Posted Date
2018-12-17
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
288
Registration Number
NCT02145182
Locations
🇧🇷

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

Phase IIa Trial of ALXN1007 for the Treatment of Non-criteria Manifestations of Antiphospholipid Syndrome

First Posted Date
2014-05-01
Last Posted Date
2017-07-13
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
9
Registration Number
NCT02128269
Locations
🇫🇷

Hopital Claude Huriez - CHU Lille, Lille, Nord, France

🇫🇷

Hôpital Cochin, Paris, France 75679, France

🇯🇵

Hokkaido University Hospital, Sapporo-shi, Hokkaido 060-8648, Japan

and more 6 locations

Safety and Efficacy Study of Sebelipase Alfa in Participants With Lysosomal Acid Lipase Deficiency

Phase 2
Completed
Conditions
Interventions
First Posted Date
2014-04-14
Last Posted Date
2019-12-04
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
31
Registration Number
NCT02112994

Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)

Completed
Conditions
First Posted Date
2014-04-04
Last Posted Date
2019-04-01
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
32
Registration Number
NCT02104219

Evaluation of Blood Brain Barrier Integrity and Structural Abnormalities in MPS IIIB Patients Using Multimodal Magnetic Resonance Imaging

First Posted Date
2014-03-18
Last Posted Date
2016-06-27
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
5
Registration Number
NCT02090179

An Open Label Extension Trial of Eculizumab in Relapsing NMO Patients

First Posted Date
2013-12-06
Last Posted Date
2022-08-23
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
119
Registration Number
NCT02003144
Locations
🇺🇸

Mayo Clinic Arizona, Scottsdale, Arizona, United States

🇺🇸

The Research Center of Southern California, Oceanside, California, United States

🇺🇸

Georgetown University Hospital, Washington, District of Columbia, United States

and more 66 locations

Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis (REGAIN Study)

First Posted Date
2013-11-28
Last Posted Date
2019-07-16
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
125
Registration Number
NCT01997229
Locations
🇺🇸

University of Alabama, Birmingham, Alabama, United States

🇺🇸

University of California San Francisco-Fresno, Fresno, California, United States

🇺🇸

University of California-Irvine, Orange, California, United States

and more 111 locations

A Randomized Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO (PREVENT Study)

First Posted Date
2013-07-04
Last Posted Date
2019-06-26
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
143
Registration Number
NCT01892345
Locations
🇺🇸

John Hopkins University School of Medicine, Baltimore, Maryland, United States

🇦🇺

University of Sydney, Brain and Mind Center, Camperdown, New South Wales, Australia

🇦🇺

St. Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia

and more 67 locations

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ALXN1007 in Healthy Male and Female Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-06-21
Last Posted Date
2014-03-31
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
16
Registration Number
NCT01883544
Locations
🇺🇸

PAREXEL Baltimore EPCU, Baltimore, Maryland, United States

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