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ALEXION PHARMACEUTICALS, INC.

ALEXION PHARMACEUTICALS, INC. logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
1992-01-01
Employees
3.8K
Market Cap
-
Website
http://www.alexion.com

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS

Phase 2
Completed
Conditions
Atypical Hemolytic Uremic Syndrome
Interventions
First Posted Date
2009-02-16
Last Posted Date
2015-07-23
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
5
Registration Number
NCT00844428

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS

Phase 2
Completed
Conditions
Atypical Hemolytic Uremic Syndrome
Interventions
First Posted Date
2009-02-16
Last Posted Date
2015-07-23
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
16
Registration Number
NCT00844545

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS)

Phase 2
Completed
Conditions
Atypical Hemolytic Uremic Syndrome
Interventions
First Posted Date
2009-02-06
Last Posted Date
2015-07-23
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
15
Registration Number
NCT00838513

Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)

Phase 1
Completed
Conditions
Hypophosphatasia (HPP)
Interventions
Biological: asfotase alfa
First Posted Date
2008-08-29
Last Posted Date
2019-04-01
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
11
Registration Number
NCT00744042
Locations
🇺🇸

Vanderbilt Children's Hospital, Nashville, Tennessee, United States

🇺🇸

Alfred I. duPont Hospital for Children, Wilmington, Delaware, United States

🇺🇸

St. John's Hospital, Springfield, Missouri, United States

and more 7 locations

Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)

Phase 1
Completed
Conditions
Hypophosphatasia (HPP)
Interventions
Biological: Asfotase Alfa
First Posted Date
2008-08-21
Last Posted Date
2019-03-29
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
6
Registration Number
NCT00739505
Locations
🇺🇸

Barnes Jewish Hospital- Washington University School of Medicine, Saint Louis, Missouri, United States

🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

🇨🇦

Department of Pediatrics & Child Health, Health Sciences Centre Winnipeg, University of Manitoba, Winnipeg, Manitoba, Canada

Safety and Efficacy Study of Eculizumab in Patients With Refractory Generalized Myasthenia Gravis

Phase 2
Terminated
Conditions
Myasthenia Gravis
Interventions
Drug: Placebo
First Posted Date
2008-08-01
Last Posted Date
2019-09-24
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
14
Registration Number
NCT00727194
Locations
🇺🇸

University of California, Irvine, Orange, California, United States

🇺🇸

Emory University, Atlanta, Georgia, United States

🇺🇸

Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

and more 22 locations

An Open-Label Treatment Protocol to Provide Continued Elvucitabine Treatment

Phase 2
Completed
Conditions
HIV Infections
Interventions
First Posted Date
2008-05-12
Last Posted Date
2023-08-14
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
7
Registration Number
NCT00675844
Locations
🇺🇸

Clinical Trial Site, Dallas, Texas, United States

Safety and Dose Ranging Study of Samalizumab to Treat Relapsing or Refractory CLL or MM

Phase 1
Terminated
Conditions
B-cell Chronic Lymphocytic Leukemia
Multiple Myeloma
Interventions
First Posted Date
2008-04-01
Last Posted Date
2019-03-05
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
26
Registration Number
NCT00648739

Safety and Efficacy Study of Eculizumab in Patients With Mild Allergic Asthma

Phase 2
Completed
Conditions
Allergic Asthma
First Posted Date
2007-06-13
Last Posted Date
2009-01-15
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
21
Registration Number
NCT00485576
Locations
🇨🇦

Hospital Laval, Ste-Foy, Quebec, Canada

🇨🇦

McMaster University, Hamilton, Ontario, Canada

The Paroxysmal Nocturnal Hemoglobinuria Early Access Treatment Protocol

Conditions
Hemoglobinuria, Paroxysmal
First Posted Date
2007-02-22
Last Posted Date
2014-05-06
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Registration Number
NCT00438789
Locations
🇺🇸

Anthony Botti, Livingston, New Jersey, United States

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