Lentiviral Hematopoietic Stem Cell Gene Therapy for MLD
- Conditions
- Metachromatic Leukodystrophy (MLD)
- First Posted Date
- 2025-07-01
- Last Posted Date
- 2025-07-01
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 10
- Registration Number
- NCT07046338
- Locations
- 🇨🇳
Shenzhen Geno-Immune Medical Institute, Shenzhen, Guangdong, China
Combination Immunotherapy Targeting Melanoma
- Conditions
- Melanoma
- Interventions
- Biological: Antigen-specific CAR T, CTL and DCvac to treat melanoma.
- First Posted Date
- 2024-12-18
- Last Posted Date
- 2024-12-18
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 30
- Registration Number
- NCT06739226
- Locations
- 🇨🇳
Shenzhen Geno-Immune Medical Institute, Shenzhen, Guangdong, China
Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells
- Conditions
- Autoimmune Diseases
- Interventions
- Biological: fetal MSCs combined with 4SCAR T cells
- First Posted Date
- 2024-05-30
- Last Posted Date
- 2024-05-30
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 30
- Registration Number
- NCT06435897
- Locations
- 🇨🇳
Shenzhen Geno-immune Medical Institute, Shenzhen, Guangdong, China
Engineered Dendritic Cell Vaccines for Multiple Myeloma
- Conditions
- Multiple Myeloma or Plasmacytoma
- Interventions
- Biological: DC vaccines
- First Posted Date
- 2024-05-30
- Last Posted Date
- 2024-06-10
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 10
- Registration Number
- NCT06435910
- Locations
- 🇨🇳
Shenzhen Geno-immune Medical Institute, Shenzhen, Guangdong, China
🇷🇺The Regional Hematology Center in Clinical Hospital No. 2 of the Ministry of Health, Vladivostok, Russian Federation
Frontline Combination CAR-T Cell Therapy for Multiple Myeloma or Plasmacytoma
- Conditions
- Multiple MyelomaPlasmacytoma
- Interventions
- Biological: CAR-T cells
- First Posted Date
- 2024-05-24
- Last Posted Date
- 2024-06-10
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 20
- Registration Number
- NCT06429150
- Locations
- 🇨🇳
Shenzhen Geno-immune Medical Institute, Shenzhen, Guangdong, China
🇷🇺Hematologist of the Regional Hematology Center in Clinical Hospital No. 2 of the Ministry of Health, Vladivostok, Russian Federation
Universal CAR-T Cells Targeting Multiple Myeloma
- Conditions
- Multiple Myeloma in Remission
- Interventions
- Biological: MM-specific universal CAR T cells
- First Posted Date
- 2023-08-23
- Last Posted Date
- 2023-10-12
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 20
- Registration Number
- NCT06006741
- Locations
- 🇨🇳
Shenzhen Geno-Immune Medical Institute, Shenzhen, Guangdong, China
Universal CAR-T Cells Targeting AML
- Conditions
- Acute Myeloid Leukemia
- Interventions
- Biological: CLL-1, CD33, CD38 and/or CD123-specific universal CAR- T cells
- First Posted Date
- 2023-08-16
- Last Posted Date
- 2023-10-12
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 30
- Registration Number
- NCT05995041
- Locations
- 🇨🇳
Shenzhen Geno-Immune Medical Institute, Shenzhen, Guangdong, China
Universal 4SCAR7U Targeting CD7-positive Malignancies
- Conditions
- T-cell Acute Lymphoblastic LymphomaNK Cell LymphomaT-cell Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia
- Interventions
- Biological: Universal CD7-specific CAR gene-engineered T cells
- First Posted Date
- 2023-08-16
- Last Posted Date
- 2023-10-12
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 30
- Registration Number
- NCT05995028
- Locations
- 🇨🇳
Shenzhen Geno-immune Medical Institute, Shenzhen, Guangdong, China
4SCAR19U T Cells Targeting B Cell Malignancies
- Conditions
- B Cell Malignancies
- Interventions
- Biological: Universal CD19-specific CAR gene-engineered T cells
- First Posted Date
- 2023-08-16
- Last Posted Date
- 2023-10-12
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 30
- Registration Number
- NCT05995015
- Locations
- 🇨🇳
Shenzhen Geno-Immune Medical Institute, Shenzhen, Guangdong, China
CAR-T Cells Targeting Autoimmune Diseases
- Conditions
- Autoimmune Diseases
- Interventions
- Biological: 4SCAR T cells
- First Posted Date
- 2022-07-15
- Last Posted Date
- 2022-07-19
- Lead Sponsor
- Shenzhen Geno-Immune Medical Institute
- Target Recruit Count
- 30
- Registration Number
- NCT05459870
- Locations
- 🇨🇳
Shenzhen Geno-immune Medical Institute, Shenzhen, Guangdong, China
🇨🇳Guilin Hospital of Chinese Traditional and Western Medicine, Guilin, Guangxi, China