CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST

Mary Catchpole, 19, becomes the first European patient to receive leniolisib (Joenja), a newly approved targeted treatment for activated PI3-kinase delta syndrome (APDS), a rare inherited immune disorder.

The NHS will be the first health system in Europe to trial histotripsy, a non-invasive ultrasound technology that destroys liver tumors using sound waves to create "bubble clouds" that pulverize cancer cells.

A groundbreaking clinical trial led by Addenbrooke's Hospital demonstrates 100% three-year survival rate for patients with BRCA-mutated breast cancer when treated with olaparib plus chemotherapy before surgery.

IgniteData, AstraZeneca, and Cambridge University Hospitals have launched the Archer platform in a Phase 3 clinical trial, automating data transfer between electronic health records and clinical trial databases.

Research analyzing 1,600 patient records shows asthma spirometry tests are 8% more reliable for each hour closer to 8:30 AM, highlighting the impact of circadian rhythms on diagnostic accuracy.

A groundbreaking UK study involving 135 children across ten pediatric intensive care units examines pressure reactivity index monitoring in traumatic brain injuries, aiming to improve treatment outcomes.

Early, intensive 'top-down' therapy with TNF blockers plus immunomodulators shows superior outcomes compared to the traditional 'step-up' approach for newly diagnosed Crohn's disease.

A six-year-old boy from Peterborough is the first UK participant in a global clinical trial for a novel drug targeting low-grade gliomas.