• Kazia Therapeutics has initiated the ABC-Pax trial to evaluate paxalisib combined with immunotherapy in advanced breast cancer patients.
• The Phase 1b study will assess the safety and efficacy of paxalisib with pembrolizumab or olaparib in triple-negative breast cancer.
• The trial utilizes a novel liquid biopsy platform for real-time monitoring of cancer and immune cell behavior during treatment.
• This combination aims to reprogram dormant cancer cells, making them susceptible to immune attack, potentially improving patient outcomes.