• A recent study published in *Nature Medicine* reveals that home-based transcranial direct current stimulation (tDCS) is a potential treatment for major depressive disorder.
• The clinical trial demonstrated that nearly half of the patients receiving tDCS achieved clinical remission, compared to just over 20% in the control group.
• The study showed a good safety profile, offering reassurance to clinicians and patients, and suggesting tDCS as a possible first-line treatment option.
• The findings support the feasibility of bringing mental health treatments into a home setting, potentially improving accessibility for patients.