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JANSSEN RESEARCH & DEVELOPMENT, LLC
🇺🇸
United States
Country
🇺🇸
United States
Ownership
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Employees
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Market Cap
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Clinical Trials
Related News
A Phase II Open Label Study of Xilonix in Subjects With Pyoderma Gangrenosum
Phase 2
Completed
Conditions
Pyoderma Gangrenosum
Interventions
Biological: Xilonix
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First Posted Date
2013-10-18
Last Posted Date
2024-12-05
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
10
Registration Number
NCT01965613
Locations
🇺🇸
XBiotech Investigative Site, Tallahassee, Florida, United States
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Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42165279 in Healthy Young and Elderly Participants
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-42165279 100 mg
Drug: JNJ-42165279 50 mg
Drug: JNJ-42165279 30 mg
Drug: Placebo
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First Posted Date
2013-10-17
Last Posted Date
2014-12-03
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
40
Registration Number
NCT01964651
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A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Patients With Advanced or Refractory Solid Tumors or Lymphoma
Phase 1
Completed
Conditions
Lymphoma
Neoplasms
Adenocarcinoma
Esophagogastric Junction
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First Posted Date
2013-10-14
Last Posted Date
2019-05-15
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
19
Registration Number
NCT01962532
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A Study of Safety and Effectiveness of JNJ-54781532 in Patients With Moderately to Severely Active Ulcerative Colitis
Phase 2
Completed
Conditions
Colitis, Ulcerative
Interventions
Drug: Placebo
Drug: JNJ-54781532 25 mg once daily
Drug: JNJ-54781532 75 mg twice daily
Drug: JNJ-54781532 75 mg once daily
Drug: JNJ-54781532 150 mg once daily
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First Posted Date
2013-10-10
Last Posted Date
2019-01-04
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
219
Registration Number
NCT01959282
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A Study to Investigate Evoked Potentials as Markers of Ketamine-induced Cortical Plasticity in Patients With Major Depressive Disorder
Phase 2
Terminated
Conditions
Major Depressive Disorder
Interventions
Drug: Placebo
Drug: Ketamine
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First Posted Date
2013-10-08
Last Posted Date
2017-01-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
13
Registration Number
NCT01957410
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A Non-drug Study Profiling Cutaneous Lupus
Completed
Conditions
Lupus Erythematosus, Discoid
Lupus Erythematosus, Cutaneous
Lupus Erythematosus, Systemic
Interventions
Procedure: No intervention, skin biopsy
Procedure: No intervention, blood collection
Procedure: No intervention, urine collection
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First Posted Date
2013-08-15
Last Posted Date
2014-09-12
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
29
Registration Number
NCT01923415
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An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Phase 2
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Placebo
Drug: CNTO 6785 100 mg
Drug: CNTO 6785 50 mg
Drug: CNTO 6785 15 mg
Drug: CNTO 6785 200 mg
Drug: Methotrexate (MTX)
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First Posted Date
2013-07-26
Last Posted Date
2016-03-02
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
257
Registration Number
NCT01909427
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An Observational Study to Assess the Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Users of Proton Pump Inhibitors, and Users of Metoclopramide
Completed
Conditions
Death, Sudden, Cardiac
Interventions
Drug: No intervention
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First Posted Date
2013-07-25
Last Posted Date
2015-05-19
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
15000
Registration Number
NCT01907633
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A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants
Phase 1
Withdrawn
Conditions
Healthy
Interventions
Drug: Metoprolol tartrate immediate-release (metoprolol IR)
Drug: JNJ-54452840
Drug: Placebo
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First Posted Date
2013-07-18
Last Posted Date
2016-11-01
Lead Sponsor
Janssen Research & Development, LLC
Registration Number
NCT01902550
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A Study to Assess the Safety and Pharmacokinetics of Subcutaneously Administered Golimumab, a Human Anti-TNFα Antibody, in Pediatric Patients With Moderate to Severe Active Ulcerative Colitis
Phase 1
Completed
Conditions
Colitis, Ulcerative
Interventions
Drug: Golimumab
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First Posted Date
2013-07-16
Last Posted Date
2023-05-11
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
35
Registration Number
NCT01900574
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