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Psychedelic Drug DOI Identifies Neuron to Reduce Anxiety in TIFR Study

• Researchers at TIFR have identified a specific neuron in the ventral hippocampus that, when activated, can alleviate anxiety in rodents. • The study used the synthetic psychedelic drug DOI to target and trace the PV-positive neuron responsible for reducing anxiety without hallucinations. • This discovery could lead to more targeted treatments and the development of psychedelic-inspired medications for treatment-resistant mental health conditions. • The research team collaborated with multiple institutions, including Cornell, Yale, and Columbia universities, to validate their findings.
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