Novel Alzheimer's Surgery Shows Promising Initial Results in China
• Chinese scientists report cognitive improvements in an Alzheimer's patient following lymphatic venous anastomosis (LVA) surgery, a novel approach to enhance brain waste clearance.
• The LVA procedure connects neck lymphatic vessels to veins, aiming to facilitate the removal of harmful beta-amyloid and tau proteins from the brain.
• Initial results showed improvements in cognitive function tests and a reduction in depression symptoms five weeks post-surgery in a 76-year-old patient.
• Researchers emphasize the need for broader studies to confirm these findings, while noting the potential of LVA as a new direction in Alzheimer's treatment research.
Phase IIb Trial Evaluates Efficacy and Safety of Anyu Peibo Capsules for Major Depressive Disorder
A 6-week, phase IIb, randomized, double-blind, placebo-controlled study conducted across nine research sites in China evaluated the efficacy and safety of Anyu Peibo capsules in treating Major Depressive Disorder (MDD). The study involved 86 patients, comparing Anyu Peibo capsules (0.8 g twice daily) against a placebo. While the primary outcome did not show a significant difference between the two groups, secondary outcomes indicated potential benefits of Anyu Peibo capsules, including improvements in HAMD-17 and HAMA scores. The treatment was found to be safe and well-tolerated, with a lower incidence of adverse events compared to other antidepressants.
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