The National Neuroscience Institute conducted a study on neurological disease response, facing ethical concerns from patients recruited without physician knowledge. The Ministry of Health appointed a Committee of Inquiry to address lapses in the ethics approval process and study conduct. The Committee identified issues including patient recruitment without physician knowledge, lack of informed consent for procedures, and modifications to treatment regimes. Recommendations include strengthening HECs, ensuring detailed study protocol submissions, and formalizing research team roles and responsibilities.