SANDOZ, INC. | MedPath

Esperion Secures Patent Protection for NEXLETOL Until 2040 Through Settlement with Micro Labs

13 days ago

• Esperion Therapeutics has reached a settlement agreement with Micro Labs that prevents the generic manufacturer from marketing a version of NEXLETOL (bempedoic acid) before April 19, 2040. • The agreement resolves patent litigation initiated by Esperion in response to Micro Labs' Abbreviated New Drug Application seeking approval for a generic version of the cholesterol-lowering medication. • Litigation against eight other ANDA filers continues, with no guarantee that these ongoing cases will prevent other generic versions from entering the market before the 2040 patent expiration.

Liquidia Secures $100M Financing to Advance Yutrepia for Pulmonary Hypertension Treatment

2 months ago

• Liquidia Corporation has amended its agreement with Healthcare Royalty to potentially add up to $100 million in financing, with an initial $25 million available at closing. • The funds will support Yutrepia's commercial development for pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD), along with clinical trials for pediatric patients. • Additional funding tranches include $50 million upon first commercial sale following FDA approval and $25 million if Yutrepia achieves over $100 million in net sales by June 2026.

Zhaoke Ophthalmology's TAB014 Shows Positive Phase 3 Results; Valo Health Shelves OPL-0401

5 months ago

• Zhaoke Ophthalmology's TAB014 met primary and key secondary endpoints in a Phase 3 trial for wet age-related macular degeneration (AMD). • Caplin Steriles received FDA approval for its generic difluprednate ophthalmic emulsion, used to treat inflammation and pain after ocular surgery. • Valo Health will seek a partner for OPL-0401, a diabetic retinopathy drug, after it failed to meet endpoints in the SPECTRA trial. • GEMMABio secured $34 million in seed funding to advance its gene therapy programs, focusing on rare diseases in Brazil.