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Ensysce Biosciences

Ensysce Biosciences logo
🇺🇸United States
Ownership
Public
Established
2008-01-01
Employees
9
Market Cap
$5.4M
Website
http://www.ensysce.com
Introduction

Ensysce Biosciences, Inc. is a clinical-stage biopharmaceutical company, which engages in the development of solutions for severe pain relief while reducing the fear of and the potential for misuse and overdose. The firm's Trypsin Activated Abuse Protection and Multi-Pill Abuse Resistance platforms are in the process of developing a new class of powerful, tamper-proof opioids that prevent both drug abuse and overdoses. The company was founded in April 2003 and is headquartered in La Jolla, CA.

Assessment of PF614 Effects on Experimental Pain in the Cold Pressure Test (PF614-201)

Phase 2
Completed
Conditions
Acute Pain
Interventions
Drug: Placebo
First Posted Date
2024-10-07
Last Posted Date
2024-10-07
Lead Sponsor
Ensysce Biosciences
Target Recruit Count
16
Registration Number
NCT06629402
Locations
🇺🇸

Dr. Vince Clinical Research, Overland Park, Kansas, United States

PF614 Analgesic Activity in Acute Postoperative Pain

Phase 3
Not yet recruiting
Conditions
Postoperative Pain
Postoperative Pain, Acute
Interventions
Drug: PF614 capsule
Drug: Placebo
First Posted Date
2024-09-19
Last Posted Date
2024-10-02
Lead Sponsor
Ensysce Biosciences
Target Recruit Count
300
Registration Number
NCT06602271

Single and Multi-Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat (PF614-MPAR-102)

Phase 1
Recruiting
Conditions
Pharmacokinetics
Interventions
Drug: PF614 capsule
First Posted Date
2024-07-15
Last Posted Date
2025-05-25
Lead Sponsor
Ensysce Biosciences
Target Recruit Count
50
Registration Number
NCT06500793
Locations
🇺🇸

Quotient Sciences, Miami, Florida, United States

A Study to Evaluate the Oral Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Phase 1
Completed
Conditions
Recreational Drug Use
Interventions
First Posted Date
2022-10-07
Last Posted Date
2023-01-05
Lead Sponsor
Ensysce Biosciences
Target Recruit Count
32
Registration Number
NCT05571345
Locations
🇺🇸

Dr. Vince Clinical Research, Overland Park, Kansas, United States

A Study to Evaluate the Intranasal Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Phase 1
Completed
Conditions
Recreational Drug Use
Interventions
First Posted Date
2022-10-05
Last Posted Date
2022-12-27
Lead Sponsor
Ensysce Biosciences
Target Recruit Count
27
Registration Number
NCT05567354
Locations
🇺🇸

Ohio Clinical Trails, Columbus, Ohio, United States

Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat

Phase 1
Completed
Conditions
Pharmacokinetics
Interventions
First Posted Date
2021-10-22
Last Posted Date
2024-01-09
Lead Sponsor
Ensysce Biosciences
Target Recruit Count
111
Registration Number
NCT05090280
Locations
🇺🇸

Quotient Sciences, Miami, Florida, United States

Evaluation of Oral PF614 Relative to OxyContin

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2021-09-14
Last Posted Date
2022-09-19
Lead Sponsor
Ensysce Biosciences
Target Recruit Count
84
Registration Number
NCT05043766
Locations
🇺🇸

PRA Health Sciences-Early Development Services, Salt Lake City, Utah, United States

Oral Nafamostat in Healthy Volunteers

Phase 1
Completed
Conditions
Pharmacokinetics
Interventions
First Posted Date
2020-05-28
Last Posted Date
2021-10-19
Lead Sponsor
Ensysce Biosciences
Target Recruit Count
17
Registration Number
NCT04406415
Locations
🇺🇸

Arizona Research Center, Phoenix, Arizona, United States

Study of PF614 Compared to OxyContin® in Healthy Volunteers (PF614-101)

First Posted Date
2015-05-27
Last Posted Date
2024-10-02
Lead Sponsor
Ensysce Biosciences
Target Recruit Count
64
Registration Number
NCT02454712
Locations
🇺🇸

PRA Health Sciences - Early Development Services, Lenexa, Kansas, United States

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