University of Cambridge

Nebulized colistimethate sodium showed mixed results in bronchiectasis and Pseudomonas aeruginosa infections, with PROMIS-I showing reduced exacerbation rates (RR 0.61) and PROMIS-II showing no difference (RR 1.00). COVID-19 disruptions in PROMIS-II were identified as the cause for the differing outcomes. A meta-analysis supported colistimethate sodium's efficacy in reducing exacerbation rates (RR 0.65). Despite inconsistent trial results, inhaled antibiotics for bronchiectasis have received conditional endorsement in guidelines.

Nxera’s oral EP4 antagonist HTL0039732, potentially treating various cancers with immunotherapies, is in a Phase 1/2a trial sponsored by Cancer Research UK. The trial, evaluating safety and anti-tumor activity, will be presented at ESMO 2024.

New wearable brain imaging tech measures whole-brain activity in babies, revealing early social processing at 5 months, potentially aiding in understanding neurodiversity.

UKRI India and the Government of India have jointly funded £19.4 million for research in farmed animal diseases, understanding geohazards, and sustainable materials. The collaboration includes projects led by UK and Indian researchers, focusing on improving farmed animal health, understanding geohazards, and developing sustainable industrial practices.

Engineering employment growth driven by renewable energy, materials science, and biotechnology. Graduate degrees enhance technical expertise, critical thinking, and leadership potential. Columbia University, National University of Singapore, and University of Cambridge offer top engineering programs with strong research emphasis and career development opportunities.

Researchers from Oxford and Cambridge developed 'origami-inspired' electrodes for minimally invasive brain surgery, reducing incision size and recovery risks. The electrodes, published in Nature Communications, start as a flat silicone wafer, fold into a compact form, and unfold inside the brain to cover a larger area. Successful tests on pigs suggest potential for diagnosing epilepsy, developing brain-computer interfaces, and treating other neurological conditions.

A Canadian family's relentless quest for a cure for their son's rare disease, SPG50, led to groundbreaking gene therapy treatment in Spain, significantly improving his condition and paving the way for others with the same condition.

A study led by Christos Davatzikos identifies 5 forms of cerebral atrophy linked to aging, detectable via machine learning. These patterns, influenced by biological traits and habits, predict dementia risk. Other research highlights inflammation's role in cognitive decline, suggesting exercise and tailored treatments as countermeasures. Overall, these studies aim to refine aging measurement and improve preventive actions.