Penn State College of Medicine, Beat Childhood Cancer Research Consortium, Four Diamonds, and Senhwa Biosciences launch a clinical trial evaluating the investigational drug silmitasertib in combination with FDA-approved drugs for solid tumors in children and young adults, focusing on neuroblastoma, Ewing sarcoma, osteosarcoma, rhabdomyosarcoma, and liposarcoma. The trial aims to establish a recommended dose, assess safety, tolerability, and efficacy, and enroll up to 114 participants nationwide. Funding is provided by the Beat Childhood Cancer Foundation and the Little Warrior Foundation.