CervoMed, Inc. is a clinical stage biotechnology company. It engages in the business of advancing CNS focused therapeutics to benefit patients with a range of degenerative diseases of the brain. The company is currently developing neflamapimod, an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. The company was founded in1995 and is headquartered in Boston, MA.
Q32 Bio's bempikibart showed promise in Phase IIa trial for alopecia areata (AA), achieving a 16% mean reduction in SALT score at week 24 compared to placebo.
CervoMed's RewinD-LB Phase 2b trial of neflamapimod in dementia with Lewy bodies (DLB) did not meet its primary or secondary endpoints.
The FDA has granted orphan drug designation to CervoMed's neflamapimod for frontotemporal dementia, a rare neurodegenerative disease.
CervoMed and Cognition Therapeutics are both advancing novel therapies for dementia with Lewy bodies (DLB) in Phase II clinical trials, addressing a significant unmet need.
CervoMed received the Prix Galien USA 2024 Best Startup award for its work on developing a treatment for Dementia with Lewy bodies (DLB).
CervoMed's neflamapimod demonstrated a significant reduction in plasma GFAP levels, a key biomarker of neurodegenerative activity in DLB patients, in a Phase 2a trial.
CervoMed's neflamapimod demonstrates potential in treating Dementia with Lewy Bodies (DLB) by reducing neurodegenerative activity in the basal forebrain cholinergic system.
CervoMed's neflamapimod demonstrated a significant reduction in plasma GFAP levels (p=0.015 vs placebo) in Phase 2a trials, suggesting reduced neurodegenerative activity in DLB.
CervoMed's neflamapimod demonstrated a significant reduction in plasma GFAP levels, a key biomarker of neurodegenerative activity in dementia with Lewy bodies (DLB).
CervoMed will present new data on neflamapimod's potential in treating dementia with Lewy bodies (DLB) at the CTAD conference.