Imperial College London

🇧🇪Belgium

Country: 🇧🇪Belgium

Ownership: Private

Established: 1907-07-08

Employees: 5K

Market Cap: -

Website: http://www.imperial.ac.uk

Clinical Trials

AI Clinician XP2 - A Study of the AI Clinician Running in Real Time in the ICU

Not yet recruiting

Conditions: Sepsis

Interventions: Other: AI Clinician

First Posted Date: 2023-02-28

Last Posted Date: 2023-02-28

Lead Sponsor: Imperial College London

Target Recruit Count: 64

Registration Number: NCT05748301

Locations: 🇬🇧
Imperial College Hospitals NHS Trust, London, United Kingdom
🇬🇧
Univeristy College London Hospitals NHS Foundation Trust, London, United Kingdom

Quantifying 18kDa TSPO Expression in the Lung in Pulmonary Artery Hypertension (PAH)

Recruiting

Conditions: Pulmonary Arterial Hypertension
Healthy

Interventions: Radiation: TSPO PET scan (11C-PBR28)

First Posted Date: 2023-02-27

Last Posted Date: 2024-10-15

Lead Sponsor: Imperial College London

Target Recruit Count: 6

Registration Number: NCT05745961

Locations: 🇬🇧
Imperial Clinical Research Facility, London, United Kingdom

THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)

Phase 4

Recruiting

Conditions: Venous Thromboembolism
Varicose Veins

Interventions: Drug: Dalteparin Sodium
Drug: Tinzaparin Sodium
Drug: Enoxaparin Sodium
Drug: Rivaroxaban
Drug: Apixaban
Drug: Dabigatran Etexilate

First Posted Date: 2023-02-21

Last Posted Date: 2025-05-02

Lead Sponsor: Imperial College London

Target Recruit Count: 6660

Registration Number: NCT05735639

Locations: 🇬🇧
Imperial College Hospital NHS Foundation Trust, London, United Kingdom

FibroLamellar Carcinoma: an International Registry Study

Not yet recruiting

Conditions: Fibrolamellar Cancer of the Liver

First Posted Date: 2023-02-16

Last Posted Date: 2023-02-16

Lead Sponsor: Imperial College London

Target Recruit Count: 200

Registration Number: NCT05730686

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma

Recruiting

Conditions: PDAC - Pancreatic Ductal Adenocarcinoma
Pancreatic Cancer

Interventions: Diagnostic Test: Breath test
Diagnostic Test: Collection of matched samples of breath, biofluids and pancreatic tissue

First Posted Date: 2023-02-14

Last Posted Date: 2025-01-27

Lead Sponsor: Imperial College London

Target Recruit Count: 963

Registration Number: NCT05727020

Locations: 🇬🇧
Imperial College Healthcare NHS Trust, London, United Kingdom

ATP and P2X3 Receptor in Chronic Cough

Not Applicable

Not yet recruiting

Conditions: Cough

Interventions: Device: Adenosine triphosphate (ATP) solution inhalation from nebuliser
Diagnostic Test: Inhalational challenge with increasing concentrations of capsaicin solutions
Device: Recording of Cough Count and frequency using the Hyfe Cough Monitor
Procedure: Collection of exhaled breath condensate
Diagnostic Test: Continuous laryngoscopic examination
Diagnostic Test: Sputum induction
Diagnostic Test: Spirometric measurements
Diagnostic Test: Blood sample collection

First Posted Date: 2023-02-06

Last Posted Date: 2023-02-06

Lead Sponsor: Imperial College London

Target Recruit Count: 20

Registration Number: NCT05713019

Preliminary Assessment of Safety and Tolerability of Dostarlimab in Combination Antiretroviral Therapy (cART) Refractory HIV Associated Kaposi Sarcoma

Phase 1

Recruiting

Conditions: Refractory HIV Associated Kaposi Sarcoma

Interventions: Drug: Dostarlimab in Combination Antiretroviral Therapy

First Posted Date: 2022-12-12

Last Posted Date: 2024-08-21

Lead Sponsor: Imperial College London

Target Recruit Count: 20

Registration Number: NCT05646082

Locations: 🇬🇧
Chelsea & Westminster Hospital, London, United Kingdom

A Feasibility Window Study of Pembrolizumab Prior to Second Evacuation for Post-molar Gestational Trophoblastic Neoplasia

Phase 2

Recruiting

Conditions: Gestational Trophoblastic Neoplasia
Gestational Trophoblastic Tumor, Recurrent
Gestational Trophoblastic Disease

Interventions: Drug: Pembrolizumab

First Posted Date: 2022-12-02

Last Posted Date: 2024-04-17

Lead Sponsor: Imperial College London

Target Recruit Count: 20

Registration Number: NCT05635344

Locations: 🇬🇧
Imperial College Healthcare NHS Trust, London, United Kingdom

Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous Disease

Not Applicable

Recruiting

Conditions: Chronic Venous Insufficiency
Iliac Vein Obstruction
Post Thrombotic Syndrome
Chronic Venous Thrombosis
Iliac Vein Stenosis

Interventions: Procedure: Deep venous stenting
Combination Product: Best medical therapy

First Posted Date: 2022-11-18

Last Posted Date: 2024-03-12

Lead Sponsor: Imperial College London

Target Recruit Count: 328

Registration Number: NCT05622500

Locations: 🇬🇧
Imperial College Healthcare NHS Trust, London, UK, United Kingdom

Imperial Prostate 7 - Prostate Assessment Using Comparative Interventions - Fast Mri and Image-fusion for Cancer

Not Applicable

Recruiting

Conditions: Prostate Cancer
Prostatic Neoplasms
Neoplasms
Prostatic Diseases
Adenocarcinoma

Interventions: Diagnostic Test: Image-Fusion targeted and systematic Biopsy
Diagnostic Test: bpMRI

First Posted Date: 2022-10-10

Last Posted Date: 2024-08-19

Lead Sponsor: Imperial College London

Target Recruit Count: 3600

Registration Number: NCT05574647

Locations: 🇬🇧
Medway Maritime Hospital, Gillingham, Kent, United Kingdom
🇬🇧
Southend University Hospital, Southend-on-Sea, Essex, United Kingdom
🇬🇧
University Hospital Southampton, Southampton, Hampshire, United Kingdom

and more 6 locations

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