Aptevo Therapeutics

🇺🇸United States
Ownership
-
Employees
40
Market Cap
-
Website
Introduction

Aptevo Therapeutics, Inc. is a clinical-stage biotechnology company, which focuses on developing novel immunotherapies for the treatment of cancer. Its pipeline APVO436, ALG.APV-527 and APVO603 were developed based on the ADAPTIR modular protein platform technology and APVO442 was developed based on the new ADAPTIR-FLE platform technology. The ADAPTIR and AD...

APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

First Posted Date
2024-10-09
Last Posted Date
2024-10-09
Lead Sponsor
Aptevo Therapeutics
Target Recruit Count
39
Registration Number
NCT06634394

ALG.APV-527 First-in-human Study

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2023-07-07
Last Posted Date
2023-07-07
Lead Sponsor
Aptevo Therapeutics
Target Recruit Count
56
Registration Number
NCT05934539
Locations
🇺🇸

Hematology Oncology Associates Of The Treasure Coast, Port Saint Lucie, Florida, United States

Study of APVO436 in Elderly or Unfit Patients With Newly Diagnosed AML

Phase 1
Withdrawn
Conditions
Interventions
First Posted Date
2021-07-22
Last Posted Date
2021-12-01
Lead Sponsor
Aptevo Therapeutics
Registration Number
NCT04973618

Study to Evaluate APVO210 in Healthy Subjects, Patients With Psoriasis, and Patients With Ulcerative Colitis

First Posted Date
2018-12-07
Last Posted Date
2021-05-19
Lead Sponsor
Aptevo Therapeutics
Target Recruit Count
85
Registration Number
NCT03768219
Locations
🇦🇺

Nucleus Network, Melbourne, Victoria, Australia

Study of ES414 in Metastatic Castration-Resistant Prostate Cancer

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-10-13
Last Posted Date
2019-08-28
Lead Sponsor
Aptevo Therapeutics
Target Recruit Count
35
Registration Number
NCT02262910
Locations
🇦🇺

Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

🇺🇸

University of Washington/Seattle Cancer Care Alliance, Seattle, Washington, United States

🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

and more 4 locations

Phase 1b Safety and Efficacy Study of TRU-016

First Posted Date
2012-07-19
Last Posted Date
2021-05-20
Lead Sponsor
Aptevo Therapeutics
Target Recruit Count
87
Registration Number
NCT01644253
Locations
🇺🇸

Eastern Regional Medical Center, Philadelphia, Pennsylvania, United States

🇺🇸

Greenville Health System, Greenville, South Carolina, United States

🇺🇸

Swedish Cancer Institute,1221 Madison St., Seattle, Washington, United States

and more 2 locations

A Study of TRU-016 in Combination With Rituximab and Bendamustine in Subjects With Relapsed Indolent Lymphoma

First Posted Date
2011-03-17
Last Posted Date
2017-06-28
Lead Sponsor
Aptevo Therapeutics
Target Recruit Count
12
Registration Number
NCT01317901
Locations
🇺🇸

Site Reference ID/Investigator# 61523, Omaha, Nebraska, United States

🇺🇸

Site Reference ID/Investigator# 61542, Augusta, Georgia, United States

🇺🇸

Site Reference ID/Investigator# 61522, Hackensack, New Jersey, United States

and more 3 locations

Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia

First Posted Date
2010-08-25
Last Posted Date
2021-06-10
Lead Sponsor
Aptevo Therapeutics
Target Recruit Count
79
Registration Number
NCT01188681
Locations
🇪🇸

For additional information regarding sites for this trial call (919) 465-4648, Navarre, Spain

Phase 1/1b Study of TRU-016 in Patients With Previously Treated CLL or Select Subtypes of Non-Hodgkin's Lymphoma

First Posted Date
2008-02-13
Last Posted Date
2017-06-28
Lead Sponsor
Aptevo Therapeutics
Target Recruit Count
96
Registration Number
NCT00614042
Locations
🇺🇸

For additional information regarding sites for this trial call 919-319-9374, Seattle, Washington, United States

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