Fujian Medical University Union Hospital
🇨🇳China
Lung Protective Ventilation Guided by Driving Pressure Improves Pulmonary Outcomes in Heart Transplant Patients
A study on patients undergoing orthotopic heart transplantation found that lung protective ventilation guided by driving pressure significantly improves pulmonary outcomes compared to conventional methods. The research highlights the importance of tailored ventilation strategies in reducing postoperative pulmonary complications.
Sacituzumab Govitecan Demonstrates Efficacy in HR+/HER2- Metastatic Breast Cancer
• Sacituzumab govitecan (SG) significantly improved progression-free survival (PFS) compared to chemotherapy in patients with HR+/HER2- metastatic breast cancer.
• The phase 3 EVER-132-002 trial included patients who had received two to four prior chemotherapy regimens, showing SG's benefit in heavily pre-treated populations.
• SG demonstrated a manageable safety profile, supporting its potential as a valuable treatment option for this patient population in regions including mainland China, Republic of Korea and Taiwan.
• The study's findings contribute to addressing the unmet need for effective therapies in HR+/HER2- metastatic breast cancer, particularly after multiple lines of treatment.
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