相关临床试验
37
4 进行中
药物批准
0
批准总数
监管机构
0
监管机构数
成立时间
1858
已完成
29
78.4%
Enrolling By Invitation
3
8.1%
尚未招募
1
2.7%
招募中
2
5.4%
Unknown
2
5.4%
暂无批准数据
- Iowa State researchers identified progranulin and the JAK2/STAT3 signaling pathway as two essential components required for myeloid progenitor cells to mature into functional macrophages. - Adding progranulin to human leukemia cells with active JAK2/STAT3 signaling successfully overcame the differentiation blockade, causing malignant cells to mature and eventually die. - The study, published in Cell Reports, also revealed two distinct embryonic macrophage populations, with only one type—dependent on both progranulin and JAK2/STAT3—showing superior tissue repair capabilities. - While years from clinical application, the findings point toward a potential therapeutic strategy of forcing leukemia cells to complete maturation rather than proliferating indefinitely.
- The National Science Foundation has awarded $15 million over two years to the RuralSTAMINA initiative, with potential for up to $160 million over 10 years, to build a bioeconomy innovation ecosystem across Nebraska and Iowa. - RuralSTAMINA brings together approximately 70 public and private partners, including the University of Nebraska-Lincoln and Iowa State University, to advance biomass conversion and biomanufacturing. - The initiative aims to develop specialty products including pharmaceuticals, animal vaccines, and biologics while creating workforce development pathways from K-12 through higher education. - The global bioeconomy market, currently valued at approximately $4 trillion, is projected to grow to $10 trillion within the next five to ten years, positioning the region for competitive advantage.
