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Higher Vitamin C Levels Linked to Preserved Brain Structure and Connectivity in Older Adults, Large Japanese Study Finds

- A cross-sectional study of 2,044 older Japanese adults found that lower plasma vitamin C levels were associated with reduced gray matter volume and weaker connectivity within the brain's default mode network. - The findings, published in PLOS ONE, represent the first direct demonstration of an association between blood vitamin C levels and structural brain network connectivity. - Researchers emphasize the observational nature of the study, noting it cannot establish causation and that the observed associations were modest compared to established risk factors like hypertension. - Maintaining optimal vitamin C levels through diet may be a simple strategy to support brain health during aging, though further longitudinal research across diverse populations is needed.