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- The CHELsea II trial, a groundbreaking cluster randomized study across 80 UK healthcare sites, aims to definitively evaluate the effects of clinically assisted hydration in patients' final days of life. - The study will assess whether maintaining hydration reduces delirium prevalence and impacts other end-of-life symptoms, targeting 1,600 participants over a two-year period ending September 2024. - This landmark trial addresses a critical evidence gap in palliative care, using standardized protocols for fluid administration and comprehensive 4-hourly patient assessments to measure outcomes.
