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Part of university of massachusetts, inc.
Clinical Trials
6
0 active
Approvals
0
Total approvals
Agencies
Regulatory bodies
Founded
1894
Completed
4
66.7%
Terminated
2
33.3%
No approval data available
- MassBiologics of UMass Medical School has initiated the first human clinical trial of Lyme PrEP, a pre-exposure prophylaxis using a single monoclonal antibody that could prevent Lyme disease. - The trial has enrolled 66 volunteers in Nebraska to evaluate safety and pharmacology, with researchers hoping to determine how long the protective antibody remains in circulation after administration. - Unlike traditional vaccines, Lyme PrEP provides immediate protection upon injection and targets Borrelia bacteria in tick guts before transmission, potentially offering a solution to a disease that affects approximately 476,000 Americans annually.