Nusantara Resources Ltd is an Australia based company. It operates in the minerals exploration sector, with the principal activity being the exploration and evaluation of gold projects. The company owns an interest in the Awak Mas Gold project (Awak Mas), located in the Luwu Regency of South Sulawesi Province, Indonesia.
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- Researchers at the National University of Singapore have developed Nanostraw Electro-actuated Transfection (NExT), a non-viral technology that efficiently delivers genetic material into immune cells with minimal disruption. - The NExT platform can transfect over 14 million immune cells in a single run with up to 94% efficiency for proteins and 80% for mRNA, while maintaining essential tumor-fighting characteristics. - This breakthrough could significantly reduce manufacturing costs and improve accessibility of CAR-T cell therapies, which currently cost approximately S$670,000 per infusion in Singapore.
- Researchers have repurposed red blood cell-derived extracellular vesicles (EVs) as nanocarriers to deliver antisense oligonucleotides (ASOs) to lung cancer cells. - The ASO-loaded EVs are engineered to target mutant Epidermal Growth Factor Receptors (EGFRs), a common driver of lung cancer, particularly in Asian populations. - This targeted approach effectively suppresses cancer progression, even in tyrosine kinase inhibitor (TKI)-resistant cells, while sparing normal tissues. - The study demonstrates a significant step towards personalized cancer medicine by customizing treatments based on individual patient cancer profiles.
