Clinical Trials
48
3 active
Approvals
0
Total approvals
Agencies
0
Regulatory bodies
Founded
1924
Active, not recruiting
1
2.1%
Completed
19
39.6%
Not yet recruiting
2
4.2%
Recruiting
7
14.6%
Terminated
4
8.3%
Unknown
5
10.4%
Withdrawn
10
20.8%
No approval data available
- Scripps Health received a $12.7 million grant from the California Institute of Regenerative Medicine to investigate scaffold-free stem cell therapy for repairing knee cartilage injuries larger than 2 square centimeters. - The research will use three-dimensional cellular spheroids made from mesenchymal stem cells that fuse together to form transplantable cartilage tissue, avoiding limitations of traditional scaffold-based approaches. - The five-year preclinical study aims to demonstrate safety and effectiveness in animal models, with plans to submit a new drug application to the FDA for potential human clinical trials. - This innovative approach could delay or eliminate the need for joint replacement surgeries and address the limited availability of donor graft tissue for current treatment options.
- Northwestern Medicine and Scripps Health have enrolled their first patients in Aclarion's pivotal CLARITY trial, bringing the total number of active enrollment sites to four out of seven approved centers. - The multi-site trial aims to evaluate whether Nociscan technology can improve surgical outcomes beyond the current 54% industry benchmark for chronic low back pain surgery patients. - The company targets enrolling 25% of the planned 300 patients by Q2 2026, with initial interim data readout expected in Q3 2026 after the first cohort completes 3-month follow-up visits.
