Clinical Trials
55
6 active
Approvals
0
Total approvals
Agencies
0
Regulatory bodies
Founded
1920
Active, not recruiting
3
5.5%
Completed
43
78.2%
Enrolling By Invitation
1
1.8%
Not yet recruiting
2
3.6%
Recruiting
4
7.3%
Unknown
2
3.6%
No approval data available
- Two convergent studies published in Early Human Development link first-trimester prenatal estrogen exposure to larger head circumference in male newborns. - A digit-ratio study of 225 newborns found higher 2D:4D ratios in boys associated with larger head circumference; a direct blood-chemistry study of 47 pregnancies confirmed the same pattern. - The findings provide the most direct empirical support yet for the estrogenized ape hypothesis, which proposes that rising prenatal estrogen drove both skeletal feminization and brain expansion in human evolution. - Researchers caution that head circumference is a proxy for brain volume, not intelligence, and that the evolutionary trade-off may carry male-specific health costs including cardiovascular problems and reduced fertility.
- A clinical trial found that ustekinumab, a drug currently used for psoriasis, preserved insulin production in young type 1 diabetes patients, with C-peptide levels 49% higher after one year compared to placebo. - Researchers discovered ustekinumab targets a specific subset of immune cells called Th17.1 cells, which make up only 0.1% of blood immune cells but play a key role in destroying insulin-producing cells. - The treatment could potentially reduce or eliminate the need for insulin injections if administered early enough, with researchers suggesting future trials combining screening and early intervention.
