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Clinical Trials
76
6 active
Approvals
0
Total approvals
Agencies
Regulatory bodies
Founded
1996
Completed
36
47.4%
Not yet recruiting
6
7.9%
Recruiting
30
39.5%
Unknown
3
4.0%
No approval data available
- Researchers used AlphaFold to design IDP1, a biodegradable protein coating that extended nanoparticle circulation time more than fourfold compared to PEG in mouse models. - An ultra-thin rigid endoscope fitting inside a 16-gauge needle delivers laser light directly into tumors, using 28% less power while maintaining efficacy. - In colon cancer-bearing mice, a single dose of IDP1-coated nanoparticles plus one laser treatment eliminated tumors within 14 days with no recurrence over 40 days. - The team plans safety studies and will test the platform in head and neck, esophageal, and pancreatic cancers reachable by endoscope.